摘要
对75例慢性肺心病患者和31例健康成年人测定了各项肺容积和最大用力呼气流量-容积曲线(MEFV)及最大用力吸气流量-容积曲线(MIFV)。结果显示:慢性肺心病患者组肺活量(VC)、补呼气容积(ERV)、一秒率(FEV1.0%)和最大呼气中段流量(MMEF)非常显著降低(P<0.01),功能残气量(FRC)、残气容积(RV)、RV/TLC%均非常显著增高(P<0.001);而最大用力吸气流量-容积曲线(MIFV)15%、25%、50%、75%、85%和MMIF各段平均流量亦有非常显著降低(P<0.001)和用力吸气时间(FIt)明显延长(P<0.001)。表明慢性肺心病患者不仅在最大用力呼时大小气道有严重的通气功能障碍。
The lung volume, the maximal force expiratory flow volume curve (MEFV) and the maximal force inspiratory flow volume (MIFV) curve were determined in 75 patients with cor pulmonale (CCP) and 31 healthy adults (HAs). It was found that: (1) vital capacity (VC), expiratory reserve volume (ERV), forced expiratory volume in one second to forced vital capacity ratio (FEV1.0%) and maximal mid expiratory flow (MMEF) were significantly decreased ( P <0.01) and functional residual capacity (FRC), residual volume (RV) and RV/TLC% were significantly increased in patients with CCP; (2) Significant decrease in 15, 25, 50, 75 and 85% of MIFV and the mean volume in each segment of MMEF ( P <0.01) and prolongation of inspiratory time ( P <0.01) were found. Our findings suggest that there are not only severe barrier in ventilational volume during the maximal force expiration but also significant decrease of mean volume in each segment of MMEF and prolongation of inspiratory time in patients with CCP.
出处
《第三军医大学学报》
CAS
CSCD
北大核心
1996年第6期536-538,共3页
Journal of Third Military Medical University
关键词
肺心病
吸气流量
容积曲线
pulmonary disease
the maximal force inspiratory flow volume curve
inspiratory time