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他克莫司治疗白癜风的研究进展 被引量:5

A Review of Tacrolimus in the Treatment of Vitiligo
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摘要 白癜风是自身免疫异常引起的色素障碍性皮肤病,他克莫司是局部治疗白癜风的一种新药,可通过抑制T细胞的激活和各种细胞因子的产生等机制阻断免疫异常,进而有效治疗白癜风。
出处 《中国皮肤性病学杂志》 CAS 北大核心 2007年第1期51-52,61,共3页 The Chinese Journal of Dermatovenereology
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参考文献17

  • 1Ongenae K,Van Geel N,Naeyaert JM.Evidence for an autoimmune pathogenesis of vitiligo[J].Pigment Cell Res,2003,16 (2):90-100.
  • 2Steitz J,Wenzel J,Gaffal E,et al.Initiation and regulation of CD8+ T cells recognizing melanocytic antigens in the epidermis:implications for the pathophysiology of vitiligo[J].Eur J Cell Biol,2004,83 (11-12):797-803.
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  • 4Grunwald MH,Ben-Amitai D,Amichai B.Macrolactam immunomodulators (tacrolimus and pimecrolimus):new horizons in the topical treatment of inflammatory skin diseases[J].J Dermatol,2004,31 (8):592-602.
  • 5Smith DA,Tofte SJ,Hanifin JM.Repigmentation of vitiligo with topical tacrolimus[J].Dermatology,2002,205 (3):301-303.
  • 6Grimes PE,Soriano T,Dytoc MT.Topical tacrolimus for repigmentation of vitiligo[J].J Am Acad Dermatol,2002,47 (5):789 -791.
  • 7Lepe V,Moncada B,Castanedo-Cazares JP,et al.A double-blind randomized trial of 0.1% tacrolimus vs 0.05% clobetasol for the treatment of childhood vitiligo[J].Arch Dermatol,2003,139 (5):581-585.
  • 8Grimes PE,Morris R,Avaniss-Aghajani E,et al.Topical tacrolimus therapy for vitiligo:therapeutic responses and skin messenger RNA expression of proinflammatory cytokines[J].J Am Acad Dermatol,2004,51(1):52-61.
  • 9Kanwar AJ,Dogra S,Parsad D.Topical tacrolimus for treatment of childhood vitiligo in Asians[J].Clin Exp Dermatol,2004,29 (6):589-592.
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