胸腺肿瘤的诊断和外科治疗

Diagnosis and surgical treatment of thymic tumor

目的总结胸腺肿瘤的诊断和外科治疗经验。方法回顾性分析1995年至2006年人住我科手术治疗的73例胸腺肿瘤患者临床资料。结果胸部X线和CT等影像学检查是诊断本病的主要手段,重症肌无力是常见的伴随症状,单纯性胸腺瘤的治疗效果优于恶性胸腺瘤和胸腺癌。结论胸腺肿瘤是低度恶性肿瘤,手术是治疗胸腺肿瘤的主要手段。术前分期与术后放化疗是影响生存的预计因素。

Objective To accumulate the experience on the diagnosis and surgical treatment of thymic tumor. Methods Seventy-three patients with thymic tumor, treated by operation in our department from 1995 to 2006, were retrospectively analyzed, which included simple thymoma resection and extended malignant thymoma and thymic carcinoma resection. Results The imaging examination, such as chest X-ray and ehest-CT, was the main diagnosis method for thymic tumor. Myasthenia gravis was common concomitant disease in the patients with thymic tumor. The therapeutic effect of the operation for simple thymoma was superior to that for malignant thymoma and thymic carcinoma. Conclusion Thymic tumor is a low potential malignancy tumor, and the main treatment for thymic tumor is to resect it as far as possible. The clinical stage before operation and the combination with other methods （ including chemotherapy and radiotherapy） after operation may improve symptoms and prolong life span in the patients with thymic tumor.