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基质细胞衍生因子-1及其受体CXCR4与乳腺癌的关系

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作者 陶金波 康骅
机构地区 首都医科大学宣武医院普外科
出处 《肿瘤防治研究》 CAS CSCD 北大核心 2007年第1期75-77,共3页 Cancer Research on Prevention and Treatment
关键词 乳腺癌 基质细胞衍生因子-1(SDF-1) CXCR4
分类号 R737.9 [医药卫生—肿瘤]
  • 相关文献

参考文献20

  • 1Kang H,Watkins G,Douglas-Jones A,et al.The elevated level of CXCR4 is correlated with nodal metastasis of human breast cancer[J].The Breast,2005,14(5):360-367.
  • 2Nagasawa T,Kikutani H,Kishimoto T.Molecular cloning and structure of a pre-B-cell growth stimulating factor[J].Proc Natl Acad Sci USA,1994,91 (6):2305-2309.
  • 3Crump MP,Gong JH,Loetscher P,et al.Solution structure and basis for functional activity of stromal cell derived factor-1:dissociation of CXCR4 activation from binding and inhibition of HIV-1[J].EMBO,1997,16(23):6996-7007.
  • 4Kantele JM,Kurk S,Jutila MA,et al.Effects of continuous exposure of stromal cell derived factor-1α on T cell rolling and tight adhesion to monolayers of activated endothelial cells[J].Immunol,2000,164 (10):5035-5040.
  • 5Kanda S,Mochizuki Y,Kanetake H.Stromal cell-derived factor-1 alpha induces tube-like structure formation of endothelial cells through phosphoinositide 3-kinase[J].Biol Chem,2003,278 (1):257-262.
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  • 7Muller A,Homey B,Soto H,et al.Involvement of chemokine receptors in breast cancer metastasis[J].Nature,2001,410 (6824):50-56.
  • 8Libura J,Drukala J,Majka M,et al.CXCR4-SDF-1 signaling is active in rhabdomyosarcoma cells and regulates locomotion,chemotaxis,and adhesion[J].Blood,2002,100 (7):2597-2606.
  • 9Tamamura H,Hori A,Kanzaki N,et al.T140 analogs as CXCR4 antagonists identified as anti metastatic agents in the treatment of breast cancer[J].FEBS Lett,2003,550 (1-3):79-83.
  • 10Kang H,Mansel R,Jiang WG.Genetic manipulation of stromal cell-derived factor-1 attests the pivotal role of the autocrine SDF-1-CXCR4 pathway in the aggressiveness of breast cancer cells[J].Int J Oncol,2005,26 (5):1429-1434.

二级参考文献16

  • 1Phillips RJ, Burdick MD, Lutz M, et al. The stromal derived factor-1/CXCL12-CXC chemokine receptor 4 biological axis in non-small cell lung cancer metastases[J]. Am J Respir Crit Care Med, 2003; 167(12) : 1676.
  • 2Geminder H, Sagi-Assif O, Goldberg L, et al, A possible role for CXCR4 and its ligand, the CXC chemokine stromal cell-derived factorl, in the development of bone marrow metastases in neuroblastoma[J]. J Immunol, 2001, 167(8):4747.
  • 3Nagasawa T, Kikutani H, Kishimoto T. Molecular cloning and structure of a pre-Prcell growth-stimulating factor [J]. Proc Natl Acad Sci USA, 1994, 91(6):2305.
  • 4Nagasawa T, Tachibana K, Kishimoto T. A novel CXC chemokine PBSF/SDF-1 and its receptor CXCR4: their functions in development, hematopoiesis and HIV infection [J]. Semin Immunol. 1998:10(3):179.
  • 5Fernandis AZ, Prasad A, Band H, et al. Regulation of CX-CR4-mediated chemotaxis and chemoinvasion of breast cancer cells [J]. Oncogene, 2004,23(1) : 157.
  • 6Muller A, Homey B, Soto H, et al. Involvement of chemokine receptors in breast cancer metastasis [J]. Nature, 2001; 410(6824) : 50.
  • 7Jiang WG, Douglas-Jones A, Mansel RE. Expression of peroxisome-proliferator activated receptor-gamma (PPARgamma) and the PPARgamma co-activator, PGC-1, in human breast cancer correlates with clinical outcomes [J]. Int J Cancer, 2003; 106(5) : 752.
  • 8Jiang WG, Watkins G, Lane J, et al. Prognostic value of rho GTPases and rho guanine nucleotide dissociation inhibitors in human breast cancers [J]. Clin Cancer Res, 2003, 9(17) : 6432.
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  • 10Yun HJ, Jo DY. Production of stromal cell-derived factor-1 (S-DF-1)and expression of CXCR4 in human bone marrow endothelial cells [J]. J Korean Med Sci, 2003; 18(5) : 679.

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肿瘤防治研究
2007年 第1期

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