磁共振成像在诊断胎儿先天性发育异常中的应用

Application of magnetic resonance imaging in prenatal diagnosis of congenital anomalies

目的:探讨磁共振成像(magnetic resonance imaging,MRI)在产前胎儿先天性发育异常诊断中的应用价值。方法:对16例B超发现胎儿发育异常者进一步行MRI检查,并与出生后体检、B超图像、尸体解剖及病理诊断结果作对比分析。结果:中枢神经系统发育异常4例,肾发育异常4例,骶尾部畸胎瘤1例,颈部肿块1例,多发畸形1例,胎儿水肿1例,腹腔囊肿1例,骨骼发育异常1例;有2例B超怀疑胎儿发育有异常,但MRI考虑为正常,出生后证实为正常新生儿。结论:MRI在胎儿检查中具有重要的临床应用价值,当B超怀疑胎儿发育有异常时MRI检查更是重要的补充手段,特别对于胎儿颅脑和肾脏发育异常有很好的诊断价值。

Objective：To explore the applled value of magnetic resonance imaging （MRI） in prenatal diagnosis, especially in congenital anomalies. Methods： In 16 fetuses with an abnormality diagnosed with ultrasonography, additional MRI was performed. MRI findings with newborn examination, ultrasonographic findings, topography and results of the pathology were compared. Results：Fetal pathologies in our study include sacrococcygeal teratoma （n=1）, neck mass （n=1）, central nervous system （CNS）abnormalities （n=4）, renal anomalies （n=4）, multipleabnormalities （n=1）, fetal hydrops （n=1）, intraabdominal cyst （n=1）, skeletal dysplasias （n=1）. Two normal fetuses were suspected by US screening while normal results were shown in the following MRI. Conclusion： MRI plays an important part in fetus examination. It is an adjuvant method when the fetal anomalies were suspected by ultrasonography, especially in the diagnosis of CNS abnormalities and renal agenesis.