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CD_4^+CD_(25)^+调节性T细胞与支气管哮喘

CD_4^+CD_(25)^+ Regulatory T Cells and Asthma
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摘要 人体内存在多种调节性T细胞,其中CD4+CD2+5调节性T细胞(CD4+CD2+5Treg)具有独特的作用方式和功能特征。CD4+CD2+5Treg在移植耐受、肿瘤免疫、过敏性疾病及微生物感染方面起着重要作用。支气管哮喘作为一种常见的慢性呼吸道疾病,其发病机制极为复杂,与免疫等多种因素有关。本文就CD4+CD2+5Treg的特性及在哮喘的发病和治疗方面研究进展作一综述。 There are many kinds of regulatory T cells in human body,in which CD4^＋CD25^＋ regulatory T cells have distinct mode of action and functional character. CCD4^＋CD25^＋ Treg are very important in transplantation tolerance, tumor immunity, anaphylactic disease and microbe infection. Asthma is a frequent chronic respiratory uact disease,whose pathogenesis is very complicated and related to multiple factors such as immunity. This review summarizes the CD4^＋CD25^＋ Treg in its biological character and its mechanism of action in pathogenesis and therapy of asthma.
作者 陶松雪 潘家华
机构地区 安徽医科大学附属安徽省立医院儿科
出处 《医学综述》 2007年第2期127-129,共3页 Medical Recapitulate
关键词 CD4^+CD25^+调节性T细胞 支气管哮喘 CD4^＋CD25^＋regulatory T cells Asthma
分类号 R562.2 [医药卫生—呼吸系统] R725.6 [医药卫生—儿科]
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医学综述
2007年 第2期

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