1Postel-Vinay MC,Finidori J.Growth hormone receptor:structure and signal transduction[J].Eur J Endocrinol,1995,133(6):654
2Kolle S,Stojkovic M,Prelle K,et al.Growth hormone (GH)/GH receptor expression and GH-mediated effects during early bovine embryogenesis[J].Biol Reprod,2001,64(6):1826
3Drop SL,Schuller AG,Lindenbergh-Kortleve DJ,et al.Structural aspects of the IGFBP family[J].Growth Regul,1992,2(2):69
4Casella SJ,Han VK,D′Ercole AJ,et al.Insulin-like growth factor Ⅱ binding to the type Ⅰ somatomedin receptor:Evidence for two high affinity binding sites[J].J Biol Chem,1986,261(20):9268
5Eva O,Michael T,Gabriel F.Transforming growth factor-1 in fetal serum correlates with insulin-like growth factor-I and fetal growth[J].Obstet Gynecol,2002,100(3):567
7Mohan S,Baylink DJ.IGF-binding proteins are multifunctional and act via IGF-dependent and independent mechanisms[J].J Endocrinol,2002,175(1):19
8Peter DG,Catherine SP.Regulation of fetal growth by the somatotrophic axis[J].J Nutr,2003,133(5):1741S
9Low LC,Tam SY,Kwan EY,et al.Onset of significant GH dependence of serum IGF-Ⅰ and IGF-binding protein 3 concentrations in early life[J].Pediatr Res,2001,50(6):737
10Itier JM,Tremp GL,Leonard JF,et al.Imprinted gene in postnatal growth role[J].Nature,1998,393(6681):125
2Janssen JA. Jacobs ML.Derkx FH,et a1.Free and total insulin-like growth factor I(IGF-I).IGF—binding proteinl(IGFBP-1),and IGFBP-3 and their relationships to the presence of diabetic retinopathy and glomerual hyperfiltration in insu lin-dependent diabetes mellitus[see comments][J].Clin Endocrinol Metab,1997,82(9):2809.
3Orskov H.Somatostatin,growth hormone, insulin-like growth factor-1, and diabetes: friends or foes[J]? Metaholism, 1996.45(8 Suppt 1) : 9l.
4Fesloff BW, Yang SX,Vaught J, et al. The insulin-like growth factor signaling system and ALS neurotrophic factor treatment strategies[J].J Neurol,1995,129(SuppI): 114.
5Smith LE,Shen W, Perruzzi C,et all Regulation of vascular endothetial growth factor-dependent retinal neovas—cularization by insulin-like growth factor-1 receptor[J].Nat Med.1999,5(12).1390.
6Danis RP. Bingamart DP. Insulin like growth factor 1 retinal microangiopathy in the pig eye[J]. Ophthalmology1997,10.1 : 1661.
7Jnnssen JA, Lamherts SW. Circulating IGF-I and its protective role in the pathogenesis of diabetic angiopathy[J],Clin Endocrinol ( Oxf), 2000, 52 (1) : 1.
3Schmidt A, Maier C,Schaller G, et al. Acute Exercise has no effect on Ghrelin plasma concentrations[J]. Horm Metab Res, 2004,36 : 174.
4Evensen KA, Vik T, Helbostad J, et al. Motor skills in adolescents with low birth weight [J]. Arch Dis Child Fetal Neonatal Ed, 2004,89 (5) : F451.
5Ranke MB. Sensitivity to IGF-1 in short children born small -or gestational age[J]. J Endocrinol Invest,2006,29 (Suppl 1) :21.
6Van Gool SA, Kamp GA, Visser-van Balen H, et al. Final height outcome following 3 years of growth hormone and gonadotropin releasing hormone agonist treatment in short adolescents with relatively early puberty[J]. J Clin Endocrinol Metab, 2007,2 : 6.
7Trivin C, Souberbielle JC, Aubertin G,et al. Diagnosis of idiopathic growth hormone deficiency: Contributions of data on the Acid-1a-bile subunit, insulin-like growth factor-1,and IGF-2, and IGFBP-3[J]. J Pediatr Endocrinol Metab, 2006,19 (4) : 481.
8Kanamoto N, Akamizu T, Tagami T, et al. Genomic structure and characterization of the 5r-flanking region of the human Ghrelin gene[J]. Endocrinology, 2004,145:4144.
9Prado CL, Pugh-Bernard AE, Elghazi L, et al. Ghrelin cells replace insulin-producing beta cells in two mouse models of pancreas development[J]. Proc Natl Acad Sci USA, 2004,101 : 2924.
10Akamizu T, Shinomiya T, Irako T, et al. Separate measurement of plasma levels of acylated and desacyl Ghrelin in healthy subjects using a new direct ELISA assay[J]. J Clin Endocrinol Metab, 2005,90 : 6.