摘要
为了解原发性肝癌肿瘤浸润淋巴细胞(TIL细胞)治疗肝癌的临床价值及应用前景,采用Rosenberg法,对TIL细胞的分离、培养及抗瘤活性进行了研究。结果8例肝癌病人的TIL细胞分离、培养均获得成功,并在培养3~5周后扩增到临床治疗肝癌所需的TIL细胞数量。抗瘤活性测定表明TIL细胞对肝癌细胞有一定的杀伤力。显示了TIL细胞治疗肝癌有一定的临床价值和应用前景。
Tumor infiltrating lymphocytes(TIL) were prepared and their tumorocidal ability tested by Rosenberg method to evaluate the effect of tumor infiltrating lymphocytes in the treatment of primary liver cancer.The results showed that the isolation and culture of TIL were successful in 8 patients,and after culturing 3 ̄5 weeks,the amount of TIL obtained was enough for the treatment of primary liver cancer.Tumorocidal ability assay showed that TIL had a stong killing effect on the cells of primary liver cancer.Our results suggested that TIL had some clinical value in the treatment of primary liver cancer.
出处
《广西医科大学学报》
CAS
1996年第4期4-6,共3页
Journal of Guangxi Medical University
基金
广西区人民政府及区教委共同资助
关键词
肿瘤浸润
淋巴细胞
原发性
生物疗法
肝肿瘤
tumor infiltrationg lymphocytes
primary liver cancer
biological therapy