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超临界流体快速膨胀法制备微细颗粒 被引量:1

The preparation of minuteness particles by rapid expansion of supercritical fluid solutions
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摘要 利用超临界流体快速膨胀法(RESS)制备微细颗粒,是近年来兴起的一种很有应用前景的新的粉体技术。笔者就该技术的过程原理、典型实验装置、过程条件的影响因素、近年来国内外的主要研究成果及其存在的问题进行了论述。 Using the technique of the rapid expansion of supercritical fluid solution,is a recent development, which is a novel and useful technique for preparing small particles. This paper discussed the fundamental principles, typical experiment apparatuses, influence factors ,application researches and some problems of the rapid expansion of supercritical technique briefly.
作者 陈华 刘亚青
机构地区 中北大学
出处 《化工科技》 CAS 2006年第6期44-48,共5页 Science & Technology in Chemical Industry
基金 国家自然科学基金资助项目(50303005)
关键词 超临界流体 快速膨胀 微细颗粒 Supercritical fluid Rapid expansion Minuteness particle
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  • 1Matson D W,Fulton J L,Petersen R C,et al.Rapid expansion of supercritical fluid solutions:solute formation of powders,thin films,and fibers[J].Ind Eng Chem Res,1987,26:2 298.
  • 2Debenedetti P G.Homogeneous nucleation in supercritical fluids[ J ].AIChE J.1990,36:1 289.
  • 3Dobbs J M,Wong J M,Johnston K P.A dry cation method for fine particales[J ].J Chem Eng Data,1986,31:303.
  • 4汪朝晖,董军航,徐南平,时钧.异丙醇铝在超临界丙烷中的溶解度与粒子制备[J].化工学报,1997,48(3):257-263. 被引量:6
  • 5Matson D W,Petersen R C,Smith R D.Production of powder sand films by the rapid expansion of supercritical solutions[J ].Journal of Materials Science,1987,22:1 919~1 928.
  • 6Williams J R,Clifford A A,Bartle K D,et al.The Production of fine particles of metal complexes using supercritical fluids[J ].Powder Technology,1998,96:158~162.
  • 7Sun Ya-Ping,Rollins H W.Preparation of polymer-protected semiconductor nanoparticles through the rapid expansion of supercritical fluid solution[ J ].Chemical Physics Letters,1998,288:585~588.
  • 8Wang Ting-Jie,Tsutsumi A,Hasegawa H,et al.Mechanism of particle coating granlation with RESS process in a fluidizedbed[J].Powder Technology,2001,118:229~235.
  • 9Mohamed R S,Debenedetti P G,Prud' homme R K.Effects of process conditionson crystals obtained from supercritical mixtures[J].Al Ch E J,1989,35(2):325~328.
  • 10Domingo C,Berends E,van Rosmalen G M.Precipitation of ultrafine organic crystals from the rapid expansion of supercritical solutionsovera capillary and a frit nozzle[J ].Ournal of Supercritical Fluids,1997,10:39~55.

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  • 1Kipp JE. The role of solid nanoparticle technology in the parenteral delivery of poorly water-soluble drugs [J]. Int J Pharm, 2004, 284 (1-2): 109-122.
  • 2Duchene D, Bochot A, Yu SC, et al. Cyclodextrins and emulsions[J].Int J Pharm, 2003, 266 (1-2) : 85-90.
  • 3Suitthimeathegorn O, Jaitely V, Florence AT. Novel anhydrous emulsions: formulation as controlled release vehicles [J]. Int J Pharm, 2005, 298 (2): 367-371.
  • 4Muller RH, Jacobs C, Kayser O. Nanosuspensions as particulate drug formulations in therapy: Rationale for development and what we can expect for the future[J]. Adv Drug Deliv Rev, 2001, 47 (1) : 3-19.
  • 5Fakes MG, Vakkalagadda B J, Qian F, et al. Enhancement of oral bioavailability of an HIV-attachment inhibitor by nanosizing and amorphous formulation approaches [J]. Int J Pharm, 2009, 370(1-2): 167-174.
  • 6Moschwitzer J, Achleitner G, Pomper H, et al. Development of an intravenously injectable chemically stable aqueous omeprazole formulation using nanosuspension technology [J]. Eur J Pharm Biopharm, 2004, 58 (3) : 615-619.
  • 7Pilcer G, Vanderbist F, Amighi K. Preparation and characterization of spray-dried tobramycin powders containing nanoparticles for pulmonary delivery [J3. Int J Pharm, 2009, 365 (1-2) : 162-169.
  • 8Mishra PR, Al Shaal L, Muller RH, et al. Production and characterization of Hesperetin nanosuspensions for dermal delivery [J]. Int J Pharm, 2009, 371 (1-2): 182-189.
  • 9Pignatello R, Bucolo C, Ferrara P, et al. Eudragit RS100 nanosuspensions for the ophthalmic controlled delivery of ibuprofen [J]. Eur J Pharm Sci, 2002, 16 (1-2): 53-61.
  • 10Muller RH, Keck CM. Drug delivery to the brain-realization by novel drug carriers [J]. J Nanosci Nanotechnol, 2004, 4(5): 471-483.

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