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细胞外信号调节激酶1/2信号通路对B淋巴细胞的影响 被引量：1

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作者 滕振平 邢飞跃
机构地区 暨南大学组织移植与免疫中心
出处 《中国药物与临床》 CAS 2007年第1期5-8,共4页 Chinese Remedies & Clinics
基金 国家自然科学基金资助项目(30471635) 广东省自然科学基金资助项目(04010451 5006033) 暨南大学引进优秀人才科研启动基金资助项目(51204058)
关键词 MAPK信号通路 细胞外信号调节激酶 B淋巴细胞 丝裂原活化蛋白激酶 刺激信号转导 ERK1/2 生物学反应 免疫性疾病
分类号 R392 [医药卫生—免疫学]
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参考文献27

  • 1Boulton TG,Nye SH,Robbins DJ,et al.ERKs:a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF.Cell,1991,65(4):663-675.
  • 2Widmann C,Gibosn S,Jarpe MB,et al.Mitogen activated protein kinase:conservation of a three kinase module from yeast to human.Physiol Rev,1999,79(1):143-180.
  • 3Richards JD,Dave SH,Chou GH,et al.Inhibition of the MEK/ERK signaling pathway blocks a subset of B cell responses to antigen.J Immunol,2001,166(6):3855-3864.
  • 4Sohn HW,Gu H,Pierce SK,et al.Cbl-b negatively regulates B cell antigen receptor signaling in mature B cells through ubiquitination of the tyrosine kinase.J Exp Med,2003,197(11):1511 -1524.
  • 5Hebeis B,Vigorito E,Kovesdi D,et al.Vav proteins are required for B-lymphocyte responses to LPS.Blood,2005,106(2):635-640.
  • 6Bone H,Eckholdt S,Williams NA,et al.Modulation of B lymphocyte signalling by the B subunit of Escherichia coli heat-labile enterotoxin.Int Immunol,2002,14(6):647-658.
  • 7Han A,Saijo K,Mecklenbr(e)uker I,et al.Bam32 links the B cell receptor to ERK and JNK and mediates B cell proliferation but not survival.Immunity,2003,19(4):621-632.
  • 8Qiang YW,Kitagawa M,Higashi M,et al.Activation of mitogen-activated protein kinase through a5/b1 integrin is required for cell cycle progression of B progenitor cell line,Reh,on human marrow stromal cells.Exp Hematol,2000,28(10):1147-1157.
  • 9Kim J,Kim HR,Lee JC.Involvement of ERK,p38 MAP kinase,and PKC in MHC class Ⅱ -mediated signal transduction in a resting B cell line.Biochem Biophys Res Commun,2002,291(1):139-145.
  • 10Piatelli MJ,Doughty C,Chiles TC,et al.Requirement for a hsp90 chaperone-dependent MEK1/2-ERK pathway for B cell antigen receptor-induced cyclin D2 expression in mature B lymphocytes.J Biol Chem,2002,277(14):12144-12150.

同被引文献11

  • 1方肇勤,侯俐,卢文丽,潘志强,廖明娟,肖芸.荷瘤小鼠证候的发生、演变、兼证及预后[J].上海中医药杂志,2007,41(1):57-62. 被引量：70
  • 2方肇勤.大鼠/小鼠实验辨证论治方法学[M].北京:科学出版社,2009:56-86.
  • 3方肇勤,潘志强,卢文丽,刘小美,侯俐,廖明娟.大鼠、小鼠常见证候计量化辨证方法的建立及其评价[J].中国中医基础医学杂志,2007,13(7):502-505. 被引量：101
  • 4Johnmra S, Oh hera M, Inabe K, et al. Regulation of Vav localization in membrane rafts by adaptor molecules Grb2 and BLNK [ J ]. Immunity, 2003,18(6) :777 -787.
  • 5Hebeis B, Vigorito E, Kovesdi D, et al. Vav proteins are required for B-lymphocyte responses to LPS [ J ]. Blood ,2005,106 (2) :635 - 640.
  • 6Marita J, Wahnsley, Steen K, et al. Critical roles forRacl and Rac2 GTPases in B cell development and signaling [ J ]. Science, 2003,302 ( 17 ) :459 - 462.
  • 7Edwards LA, Thiessen B, Dragowska WH, et al. Inhibition of ILK in PTEN-mutant human glioblastomas inhibits PKB/Akt activa-tion,induces apoptosis, and delays tumor growth [J]. Oncogene, 2005,24 (22) :3596 - 3605.
  • 8SongG, Ouyang G, Bao S. The activation of Akt/PKB signaling pathway and cell Survival [ J ]. J Cell Mol Med ,2005,9 (1) :59 -71.
  • 9Maurer U, Charvet C,Wagman, et al. Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL- 1 [J]. Molec Cell,2006,21:749-760.
  • 10Vincent T, Kukalev A, Andang M, et al. The glycogen synthase kinase (GSK) 3-beta represses RNA polymerase Ⅰ transcription [ J ]. Oncogene ,2008,27:5254 - 5259.

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中国药物与临床
2007年 第1期

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