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铜绿假单胞菌对β-内酰胺类抗生素的耐药机制和检测方法 被引量：3

Mechanism and Detection of β-lactam Antibiotic Resistance in Pseudomonas aeruginosa
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摘要 铜绿假单胞菌对β-内酰胺类抗生素产生耐药性的机制主要为产生β-内酰胺酶、主动外排系统、形成生物膜、膜的通透性降低。进行耐药酶表型和耐药酶基因的检测对防止耐药菌的产生及传播具有重要意义。本文就耐药机制及检测方法作简要综述。 The mechanism of β- lactam antibiotic resistance in Pseudomonas aeruginosa mainly includes the production of beta- lactamase, active efflux system, biofilm formation, impermeable outer membrane. To detect phenotype and genotype of beta- lactamase plays an important role in avoiding production and dissemination of β- lactam antibiotic-resistant P. aeruginosa.
作者 陈建国 李国明
机构地区 广东医学院微生物学教研室
出处 《国外医药（抗生素分册）》 CAS 2007年第1期14-18,共5页 World Notes on Antibiotics
关键词 铜绿假单胞菌 Β-内酰胺类 耐药 检测 Pseudomonas aeruginos beta- lactam resistance detection
分类号 R978.11 [医药卫生—药品]
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参考文献20

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国外医药（抗生素分册）
2007年 第1期

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