细菌L型与喉癌关系的研究

STUDY OF INFECTION OF BACTERIAL L-FORMS IN RELATION TO HUMAN LARYNGEAL CARCINOMA

用组织切片革兰氏染色、免疫组织化学染色等方法，对８５例喉癌重新切片，进行细菌Ｌ型检查，结果发现有６５例革兰氏染色Ｌ型菌阳性，其阳性率为７６．５％。５３例（６４．７％）Ｌ型抗体免疫组化染色和革兰氏染色Ｌ型菌均阳性，两者总符合率为８３．５％。细菌Ｌ型呈多形性，分布于癌巢、癌间质，常聚集成堆，也可呈散在性分布。５８例（６８．２％）癌细胞胞浆内也见到Ｌ型菌。提示细菌Ｌ型感染与喉癌关系密切。

cases with laryngeal carcinoma were studied in order to detect infection of bacterial L-forms by Gram's and immunohistochemical staining(ABC).The results showed that the infection of bacterial L-forms had been found in 65 cases with Gram's staining.The positivity rate of the infeetion bacterial L-forms was 76.5%in 85 cases,Among them,53 cases(64.7%)were positive in Gram's staining and immunohistochemical staining.The L-forms were higher pleomorphic,and localised within carcinoma nest or distributed carcinoma stroma sporadically. The L-forms localised within carcinoma cell in 58 cases(68.2%)have been observed through microscope.It suggests that the infection of bacterial L-forms in laryngeal tissues is correlated with human laryngeal carcinoma.