摘要
目的:为了观察奥曲肽(善得定)治疗重症非静脉曲张性上消化道大出血的疗效,本文总结了40例重症非静脉曲张性上消化道大出血的治疗结果,所观察者均为高龄及手术高危患者。方法:本组患者均给予奥曲肽治疗,剂量为100μg,每6小时一次,静脉滴注,持续应用3天。结果:40例中,37例出血停止,总止血率为92.5%,仅3例无效(其中2例施行手术治疗,1例死亡)。未发现明显的毒副反应。结论:奥曲肽不仅对静脉曲张性出血有效,且对非静脉曲张性消化道大出血如炎症、溃疡、血管畸形引起的出血亦有较好的疗效,可降低急诊手术率和死亡率.
Purpose:To evaluate the effects of octreotide in the
treatment of massive non-variceal upper gastrointestinal haemorrhage,40 patients were treated
with octreotide. Materials and methods:All patients were of high surgical risk on theirage and
debility,in particular,those accompanied by other systemic diseases.Octre-otide was given at a
dosage of l00μg intravenously once every six hours for 3 days.Results: Bleeding was
controlled in 37 cases,2 were treated surgically afterwards and ldeceased. No side effects were
found. Octreotide is effective not only in the treatmentof variceal bleeding,but also in severe
non-variceal hemorrhage due to inflammation,ulceration, angiodysplasia,the operative and
mortality rate can thus be decreased.
出处
《中华消化杂志》
CAS
CSCD
北大核心
1996年第5期265-267,共3页
Chinese Journal of Digestion
关键词
奥曲肽
非静脉曲张性
消化道大出血
治疗
Octreotide Non-variceal upper
gastroientestinal tract bleedi-ng Therapy