摘要
目的：观察不同营养负荷下重组人生长激素（rhGH）对腹部大手术后病人机体代谢所产生的影响。方法：将32例病人随机分为三组：即A组（低热量组）11例，用83．68kJ／（kg·d）营养支持；B组（低热量加rhGH组）10例，术后第1～7天用83．68kJ／（kg·d）＋rhGH4U／d营养支持；C组（高热量加rhGH组）11例，术后第1～7天用125．52kJ／（kg·d）＋rhGH4U／d营养支持。术后观察病人尿氮排出量的变化、血清清蛋白和前清蛋白水平。结果：术后第8天B组和C组血清前清蛋白明显高于A组（P〈0．05），其中C组明显高于B组（P〈0．05）。术后第1～8天各组尿氮排出量均大于术前。术后第4天开始，B组和c组尿氮排出量减少，与A组比差异有显著性意义。术后第8天C组尿氮排出较B组下降更明显。结论：在腹部大手术后应用rhGH的条件下，适度地增加营养负荷，可以达到较好的效果。
Objective ： To investigate the metabolic response of different load of nutrition and recombinant human growth hormone （rhGH）after major abdominal surgery. Methods：32 patients were randomly divided into three groups as fellows：Group A ： low calorie load,83.68 kJ/（kg · d） ; Group B： low calorie load combined with rhGH,83.68 kJ/（kg · d） and rhGH 4 U/d from d1 -7 after operation; Group C ： high calorie load combined with rhGH, 125.52 kJ/（ kg · d） and rhGH 4 U/d from d1 - 7 after operation. The levels of serum albumin and prealbumin and the excretion of urea nitrogen in urine were measured. after operation. Results ： On day 8 after operation, the level of prealbumin in group B and C were higher than in group A （ P 〈 0.05） , and the level in group C was higher than in group B （ P 〈 0.05 ）. On day 8 after operation, the excretion of urea in urine nitrogen was lower in group C than in group B. Conclusion：It might be better to reasonably increase the load of nutrition under the use of rhGH to better improve nutritional status after major abdominal surgery.
出处
《肠外与肠内营养》
CAS
2007年第1期10-12,17,共4页
Parenteral & Enteral Nutrition
基金
常州市科技局资助项目(CS2001904)
