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过滤型络合铜纳米高分子复合材料输精管节育器对雄犬精液的影响 被引量:12

Influence of Filtering Nano-copper Complex/polymer Composites Intravas Device on the Semem of Male Dog
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摘要 目的:验证过滤型络合铜纳米高分子复合材料输精管节育器(IVD)对雄犬的节育作用。方法:选雄性成年Beagle犬6只,手术植入IVD,术后1个月、3个月、6个月和12个月各采集犬精液,分别检测精子密度、精子活动力和精浆α-糖苷酶,并以仅做假手术的对照组(2只)作对照。结果:手术植入IVD后,雄犬精液中精子含量显著下降,3个月后精液中没有检测到活精子。结论:植入过滤型络合铜纳米高分子复合材料IVD可显著降低雄犬精液中精子的密度和活动力,是一种值得进一步研究的非阻塞性IVD。 Objective: To proof the comtra ceptive effect of the filtering nano-copper complex/polymer composites intravas device (IVD) in dogs. Methods: Eight male adult beagel dogs were collected, 6 of them were planted with IVD in their vas deferens and 2 as the control. Their semen were collected to test sperm densities, sperm activities in 1 month, 3 months, 6 months and 12 months after the operation. Results: The densities of sperms were reduced significantly after the IVD was implanted, no viable sperms were found in the 3rd month. Conclusion: The filtering nano-copper complex/polymer composites IVD can reduce the densities of dog's sperms significantly.
出处 《生殖与避孕》 CAS CSCD 北大核心 2007年第1期31-33,37,共4页 Reproduction and Contraception
基金 2004年华中科技大学医工 医理交叉科研基金 湖北省人口与计划生育委员会科研基金资助(2005-2)
关键词 纳米 CA^2+ 输精管 节育器 nano copper ions vas deferens contraception device dog
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参考文献7

  • 1Kapur MM, Mokkapati S, Farooq A, et al. Copper intravas device (IVD) and male. Contraception, 1984, 29(1 ): 45-54.
  • 2于宁妮,张适.Cu^(2+)对大鼠精子运动的影响[J].生殖与避孕,1989,9(3):37-41. 被引量:3
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  • 7Song L, Gu Y, Lu W, et al. A phase Ⅱ randomized controlled trial of a novel male contraception, an intra-vas device. Int J Androl, 2006, 29(4):489-95.

二级参考文献1

  • 1徐铎,蔡文娟,张凤娥,宋淑秀,宗文萍,董彩金,樊瑞琴.输精管铜节育器对大鼠生育力的影响[J]生殖与避孕,1985(04).

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