摘要
目的评价糖皮质激素治疗Eales病血管炎症活动期的疗效及意义。方法回顾性分析我院1996年1月至2004年12月门诊及收治的Eales病患者42只眼。依据治疗方案的不同分为激素治疗组(22只眼)以及对照组(20只眼),随访3~52个月,评价各组的治疗效果。结果两组患者比较,视力提高、视力下降均有统计学差异显著。激素组治愈率90.9%(20只眼);新生血管及牵引性视网膜脱离9.1%(各1只眼),视力提高63.6%(14只眼)。对照组20只眼,出现新生血管5只眼、牵引性视网膜脱离3只眼,反复玻璃体出血3只眼、共11只眼占55%。结论Eales病血管炎症活动期使用糖皮质激素效果确实、可靠,尽早应用糖皮质激素是减少并发症、保持较好视功能的理想方法。
Objective To estimate the therapeutic effects of glucocorticoid in the treatment of eales disease in vasculitis stage. Methods 42 eyes of eales disease patients cases which were admitted from 1996 to 2004 were ahalyzed retrospectively. According to the condition of ghcocorticoid, 42 eyes were divided into the glucocorticoid-treatment group (22 eyes) and the control group (20 eyes) and the therapeutic effects were compared. Following up for 3-52 months. Results There was significant difference in effective rate and prognosis of complication between two groups. 90.9% (20 eyes) of the glucocorticoid-treatment group were healing well. 55% (11 eyes ) of the control group brought about complications. Conclusion Glucocorticoid in the treatment of eales disease in vasculitis stage is valid and reliable. Application of glucocorticoid for Eales' disease in the early vasculitis stage is a good way to decrease complications.
出处
《中国实用眼科杂志》
CSCD
北大核心
2007年第1期112-115,共4页
Chinese Journal of Practical Ophthalmology
基金
全军“十五”指导令性课题项目(N0.04M042).吴阶平医学基金会资助项目(N0.2003-32-D)