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糖皮质激素治疗Eales病血管炎症期疗效的评价 被引量:1

The therapeutic effect of glucocorticoid in the treatment of Eales' disease in vasculitis stage
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摘要 目的评价糖皮质激素治疗Eales病血管炎症活动期的疗效及意义。方法回顾性分析我院1996年1月至2004年12月门诊及收治的Eales病患者42只眼。依据治疗方案的不同分为激素治疗组(22只眼)以及对照组(20只眼),随访3~52个月,评价各组的治疗效果。结果两组患者比较,视力提高、视力下降均有统计学差异显著。激素组治愈率90.9%(20只眼);新生血管及牵引性视网膜脱离9.1%(各1只眼),视力提高63.6%(14只眼)。对照组20只眼,出现新生血管5只眼、牵引性视网膜脱离3只眼,反复玻璃体出血3只眼、共11只眼占55%。结论Eales病血管炎症活动期使用糖皮质激素效果确实、可靠,尽早应用糖皮质激素是减少并发症、保持较好视功能的理想方法。 Objective To estimate the therapeutic effects of glucocorticoid in the treatment of eales disease in vasculitis stage. Methods 42 eyes of eales disease patients cases which were admitted from 1996 to 2004 were ahalyzed retrospectively. According to the condition of ghcocorticoid, 42 eyes were divided into the glucocorticoid-treatment group (22 eyes) and the control group (20 eyes) and the therapeutic effects were compared. Following up for 3-52 months. Results There was significant difference in effective rate and prognosis of complication between two groups. 90.9% (20 eyes) of the glucocorticoid-treatment group were healing well. 55% (11 eyes ) of the control group brought about complications. Conclusion Glucocorticoid in the treatment of eales disease in vasculitis stage is valid and reliable. Application of glucocorticoid for Eales' disease in the early vasculitis stage is a good way to decrease complications.
出处 《中国实用眼科杂志》 CSCD 北大核心 2007年第1期112-115,共4页 Chinese Journal of Practical Ophthalmology
基金 全军“十五”指导令性课题项目(N0.04M042).吴阶平医学基金会资助项目(N0.2003-32-D)
关键词 糖皮质激素 EALES病 glucocorticoid Eales' disease
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参考文献17

  • 1Atmaca LS,ldli A,Gunduz K.Visualisation of retinal vasculitis in Eales disease.Cal Inmunl In Ianm,1993; 1,41-48
  • 2罗成仁.视网膜静脉周围炎临床释义[J].Chin J Ocul Funds Dis,(4):272-272.
  • 3Jyotirmay Biswas,MS,Tarun Sharma,MS,et al:Eales disease an update.Surv Ophthalmol,2002,47:197-214
  • 4Ohno S,Mizuki N.Molecular genetics of posterior uveitis.Int Ophthalmol Clin 1995,35:21-32
  • 5Sulochana KN,Biswas J,Ramakrishnan S:Eales disease:increased oxidation and peroxidation products of membrane constituents chiefly lipids and decreased antioxidant enzymes and reduced glutathione in vitreous.Curr Eye Res 1999,19:254-9
  • 6Charmis J.On the classification and management of the evolutionary course of Eales disease.Trans Ophthalmol Soc UK,1965,85:157
  • 7Moser LA,Simpson DE,Young DD:Retinal macroaneurysms:the natural history in four patients.Optom Vis Sci 1989,66:877-83
  • 8Bas T,Biswas J,Kumar A,et al.Eales disease.Indian J Ophthalmol,1994;42(1)3-18
  • 9Woods AC:Clinical and experimental observations on the use of ACTH and cortisone in ocular inflammatory disease J Ophthalmol,1950,33:1325~1349
  • 10Howe LJ,Stanford MR,Edelsten C,et al.The efficacy of systemic coticosteroids in sight-threatening retinal vasculitis.Eye,1994;8:443-447

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  • 1Biswas J,Sharma T,Gopal L,et al.Eales disease-An update.Surv Ophthalmol 2002;47(3):197-214.
  • 2Chatzoulis DM,Theodosiadis PG,Apostolopoulos MN,et al.Retinal perivasculitis in an immunocompetent patient with systemic herpes simplex infection.Am J Ophthalmol 1997;123(5):699-702.
  • 3Sulochana KN,Rajesh M,Ramakrishnan S.Purification and characterization of a novel 88 kDa from serum and vitreous of patients with Eales disease.Exp Eye Res 2001;73(4):547-555.
  • 4Awasthi P,Mehrotra ML,Srivastava SN.Ocular conditions in pulmonary tuberculosis patients in India.Acta XX Concilium Ophthalmologicum 1966:1025.
  • 5Madhavan HN,Theres KL,Gunisha P,et al.Polymerase chain reaction for detection of Mycobacterium tuberculosis in epiretinal membrane in Eales disease.Invest Ophthalmol Vis Sci 2000;41(3):822-825.
  • 6Biswas J,Therese L,Madhavan HN.Use of polymerase chain reaction in detection of mycobacterium tuberculosis complex DNA from vitreous sample of Eales disease.Br J Ophthalmol 1999;83(8):994.
  • 7Patnaik B,Kalsi R.Understanding and management of Eales disease.Acta XX Concilium Ophthalogicum 1987;2200.
  • 8Fountain JA,Werner RB.Tuberculous retinal vasculitis.Retinal 1984;4(1):48-50.
  • 9余路珍.眼底病.济南:山东科学技术出版社 1994:82.
  • 10易长贤,谢媛媛,欧杰雄,于强.特发性视网膜血管炎的临床特征[J].中国实用眼科杂志,2003,21(2):102-104. 被引量:9

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