超声引导下注射凝血酶对医源性股动脉假性动脉瘤的治疗

Value of application of ultrasound guided thrombin injection for treatment of iatrogenic femoral arterial pseudoaneurysme

目的：探讨超声引导下注射凝血酶治疗医源性股动脉假性动脉瘤（PA）的应用价值。方法：使用22G细针穿刺，对8例医源性股动脉PA患者进行超声引导下瘤内注射凝血酶治疗，用二维超声及彩色多普勒观察瘤体内血栓形成情况，每次注入凝血酶100IU，凝血酶总用量不超过500IU，直至血栓形成。结果：8例患者均经一次性治疗成功，凝血酶用量100～500IU，血栓形成时间0．5～1．5min，无一例出现血管内血栓形成、感染、过敏等并发症。结论：超声引导凝血酶注射治疗股动脉PA安全有效，可作为经股动脉途径介入诊疗术所致医源性PA的首选治疗。

Objective：To explore the value of ultrasound guided thrombin injection （UGTI） for treatment of iatrogenic femoral arterial pseudoaneurysms （PA）. nethod：A 22-gauge needle was punctured into the PA lumen with guidance. Eight patients who had iatrogenic PA were treated with direct thrombin injection under color Doppler and 2D sonographic visualization. Result： All patients had PA thrombosis after the first procedure. The thrombosis time was 0. 5-1.5 minutes. No thromboembolic, infectious, allergic complications occurred. Conelusion：UGTI is safe and effective as the first-line therapy of iatrogenic PA following femoral arterial puncture for PCI.