摘要
目的:优化五味子的提取工艺。方法:以五味子醇甲、五味子酯甲、五味子甲素、五味子乙素含量为指标,考察提取溶剂、药材破碎程度对提取工艺的影响,优选提取工艺参数。结果:五味子药材破碎后以乙醇提取,其活性成分可得到有效利用。优化的提取工艺参数为:药材破碎过40目筛、70%乙醇提取2次、每次提取2.0h。结论:本工艺比目前配方颗粒采用的工艺合理,使质量得到了最大保证。
OBJECTIVE: To optimize the extraction process of Fructus Schisandrae Chinensis. METHODS: Taking the contents of schizandrin, schisantherin A, deoxyschizandrin, r- schizandrin as the indexes, the influence on the extraction process by extract solvent and medicinal material particle diameter was examined, and the extraction parameters were optimized. RESULTS: Active components of Fructus Schisandrae Chinensis, after the medicinal material being crushed, can be effectively utilized through extracting by alcohol. The optimized extraction parameters were as follows: the medical material being ground into 40 meshes, extracted twice by 70% alcohol, 2 hours per time. CONCLUSION: The optimized extracting process works better than current technique adopted for formulated granule preparation, and can ensure quality to the highest degree.
出处
《中国药房》
CAS
CSCD
北大核心
2007年第6期424-426,共3页
China Pharmacy
基金
江苏省135工程重点人才资助项目(65RC2002065)
关键词
五味子
提取工艺
优化
Fructus Schisandrae Chinensis
Extracting process
Optimize