白藜芦醇及其抗肿瘤作用机制

Effect and mechanism of resveratrol on anticancer

白藜芦醇（Res）是一种天然植物补体，具有抗肿瘤活性。研究表明，它可以通过抗氧化、抑制细胞色素P450酶、抑制环氧化酶（COX）、促进肿瘤细胞凋亡和诱导肿瘤细胞分化等来发挥抗癌作用。Res不仅直接作用于肿瘤细胞，而且可提高机体细胞与体液免疫应答的水平，调节细胞因子的分泌，从而发挥抗肿瘤作用。体内研究表明，Res无明显毒副作用，是一种有效的化疗和预防药物。因此，作为一种理想的天然化疗药物，将有希望用于肿瘤临床治疗。

Rcsvcratrol, a natural vegetable complement, has recently been demonstrated to be an anticancer drug. Its anticanccr effects may mediated by antioxidization, inhibiting cytochrome P450 enzymes and cyclooxygenase, promoting apoptosis , and inducing the differentiation of tumor cells, Simultaneously by enhancing immune response to cancer, and adjusting cytokine secretion. Resveratrol is a kind of effective chemical for tumor treatment and prevention with no toxieo-and by-effect in vivo. As an ideal natural chemical medicine, it＇ s likely to be used as an anticancer drug clinically in the future.