老年急性脑卒中并发肺部感染相关因素及病原学分析

Risk factors and pathogenesis analysis in elderly stroke patients associated with pulmonary infection

目的讨老年脑卒中患者合并肺部感染的危险因素及病原学特点及药敏情况。方法对115例老年脑卒中患者,回顾性分析其中确诊并发肺部感染45例的发生率与年龄、基础病、意识障碍、侵入性检查的关系及肺部感染病原菌及药敏情况。结果老年脑卒中患者合并肺部感染发病率高,与患者意识障碍及多种因素有关,病原菌以G-杆菌为主,亚胺培南对G-、G+菌敏感率最高,哌拉西林、阿米卡星亦有较高敏感率。结论老年脑卒中合并肺部感染是多种因素的结果,感染以G-杆菌为主,了解脑卒中合并肺部感染的发病因素及病原菌特点对治疗老年脑卒中有重要意义。

Objective To study the risk factors and pathogenesis of pulmonary infection in elderly stroke patients. Methods A retrospective analysis in elderly acute stroke patients was taken to investigate the rate of pulmonary infection and its relation with age, the underlying disease, disturbance of consciousness, invasive operation and the prognosis. Results The rate of pulmonary infection in elderly stroke patients was high and related to many factors including disturbance of consciousness, age, primary diseases, and invasive examination etc. The most iofective bacterium were Gram-negative bacteria. The sensitive of imipenem was the highest to Gram-negative bacteria anti Gram-positive bacteria. Amikacin and piperacillin were highly sensitive also. Conclusion The pulmonary infection in elderly cerebral apoplectic patients is caused by many factors,of which Gram-negative bacteria are main. To investigate the risk factor and pathogenio bacteria is helpful to treating elderly cerebral apoplexy,