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他克莫司治疗白癜风的现状和机制 被引量:9

Current opinion and mechanisms of tacrolimus in the treatment of vitiligo
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摘要 自2002年首次报道他克莫司软膏治疗白癜风以来,该药治疗白癜风的现状和疗效陆续见诸文献。为了全面了解该药,笔者对他克莫司软膏治疗白癜风的治疗现状、治疗机制及该药在治疗白癜风中存在的问题进行了综述。
作者 常建民
出处 《临床皮肤科杂志》 CAS CSCD 北大核心 2007年第2期123-124,共2页 Journal of Clinical Dermatology
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参考文献14

  • 1Smith DA,Tofte SJ,Hanifin JM.Repigmentation of vitiligo with topical tacrolimus[J].Dermatology,2002,205(3):301-303.
  • 2Grimes PE,Soriano T,Dytoc MT.Topical tacrolimus for repigmentation of vitiligo[J].J Am Acad Dermatol,2002,47(5):789-791.
  • 3Tanghetti EA.Tacrolimus ointment 0.1% produces repigmentation in patients with vitiligo:results of a prospective patient series[J].Cutis,2003,71(2):158-162.
  • 4Kanwar AJ,Dogra S,Parsad D.Topical tacrolimus for treatment of childhood vitiligo in Asians[J].Clin Exp Dermatol,2004,29(6):589-592.
  • 5Silverberg NB,Lin P,Travis L,et al.Tacrolimus ointment promotes repigmentation of vitiligo in children:a review of 57 cases[J].J Am Acad Dermatol,2004,51(5):760-766.
  • 6Passeron T,Ostovari N,Zakaria W,et al.Topical tacrolimus and the 308-nm excimer laser:a synergistic combination for the treatment of vitiligo[J].Arch Dermatol,2004,140(9):1065-1069.
  • 7Kawalek AZ,Spencer JM,Phelps RG.Combined excimer laser and topical tacrolimus for the treatment of vitiligo:a pilot study[J].Dermatol Surg,2004,30(2Pt 1):130-135.
  • 8Lepe V,Moncada B,Castanedo-Cazares JP,et al.A doubleblind randomized trial of 0.1% tacrolimus vs 0.05% clobetasol for the treatment of childhood vitiligo[J].Arch Dermatol,2003,139(5):581-585.
  • 9Grimes PE,Morris R,Avaniss-Aghajani E,et al.Topical tacrolimus therapy for vitiligo:therapeutic responses and skin messenger RNA expression of proinflammatory cytokines[J].J Am Acad Dermatol,2004,51(1):52-61.
  • 10Lan CC,Chen GS,Chiou MH,et al.FK506 promotes melanocyte and melanoblast growth and creates a favourable milieu for cell migration via keratinocytes:possible mechanisms of how tacrolimus ointment induces repigmentation in patients with vitiligo[J].Br J Dermatol,2005,153 (3):498-505.

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