水乐维他对严重烧伤病人白细胞趋向性及吞噬力的影响

Effect of soluvit for leucocyte tropism and phagocytic power in severe burned patients

目的 探讨水乐维他对严重烧伤病人白细胞趋向性及吞噬功能的影响。方法 选择非手术严重烧伤病人87例．随机分为水乐维他治疗组和对照组。其中，水乐维他治疗组于伤后第1天输注水乐维他，2支／d，连续2周。分别于伤后第7、14天抽取静脉血提取白细胞做趋向性及吞噬力测定。结果 水乐维他治疗组与对照组白细胞的趋向游走距离在第7天[（33±5）min，（32±8）min，P〈0．05]和在第14天[（29±6）min，（26±5）nm，P〈0.01]，均有统计学意义。而白细胞的吞噬细菌率在第7天（48．5％，43．2％，P〉0．05）和在第14天（53．7％，45.1％，P〉0.05），两组间比较差异均无统计学意义。结论 水乐维他在严重烧伤病人能增强白细胞的趋向游走能力。对增强机体免疫力有一定作用。

Objective To investigate the effect of soluvit for white blood cells tropism and phagocytic power in severe burned patients. Methods There were 87 nonoperative severe burned patients which were divided soluvit treatment groups and non - soluvit treatment groups randomly. Patients in soluvit treatment groups were treated with two bottles of soluvit per day from the first day to the fourteenth day postburn. White blood cells were extracted for testing tropism distance and phagocytic power on the 7th day and 14th day postburn respectively. Results White blood cells tropism distance in soluvit treatment groups was farer than that in non - sol- uvit treatment groups on both the 7th day postburn（33±5）mm vs（32± 8）mm（ P 〈0.05）and the 14th day （29 ± 6）mm vs （26 ±5 ）mm（ P 〈 0.01 ）. In contrast, the phagocytic power was no significant difference in both groups （ P 〉 0.05 ）. Conclusion Above results suggest that soluvit can enhance white blood cells tropism function in severe burned patients.