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多囊肾病慢性进展的分子发病机制及治疗对策 被引量:10

Molecular pathogenesis of chronic advancementin polycystic renal disease and its treatmentstrategy
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作者 梅长林 戴兵
出处 《中国实用内科杂志》 CAS CSCD 北大核心 2007年第1期53-55,共3页 Chinese Journal of Practical Internal Medicine
关键词 多囊肾病 分子发病机制 药物干预 Polycystic kidney diseases Molecular pathogenesis Drugs intervention
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参考文献15

  • 1Wilson PD.Polycystic kidney disease[J].N Engl J Med,2004,350 (2):151-164.
  • 2戴兵,刘亚伟,梅长林.纤毛与肾囊肿性疾病[J].中华肾脏病杂志,2006,22(2):129-132. 被引量:3
  • 3Nauli SM,Alenghat FJ,Luo Y,et al.Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells[J].Nat Genet,2003,33 (2):129-137.
  • 4梅长林,王文靖.多囊肾病的诊断及治疗进展[J].中国实用内科杂志,2005,25(11):969-971. 被引量:12
  • 5梅长林,戴兵.常染色体显性多囊肾病:挑战与策略[J].中华肾脏病杂志,2005,21(11):636-637. 被引量:13
  • 6Gattone VH,Wang X,Harris PC,et al.Inhibition of renal cystic disease development and progression by a vasopressin V2 receptor antagonist[J].Nat Med,2003,9 (10):1323-1326.
  • 7Bennett WM.V2 receptor antagonists in cystic kidney diseases:an exciting step towards a practical treatment[J].J Am Soc Nephrol,2005,16 (4):838-839.
  • 8Shillingford JM,Murcia NS,Larson CH,et al.The mTOR pathway is regulated by polycystin-1,and its inhibition reverses renal cystogenesis in polycystic kidney disease[J].Proc Natl Acad Sci U S A,2006,103 (14):5466-5471.
  • 9Mostov KE.mTOR is out of control in polycystic kidney disease[J].Proc Natl Acad Sci USA,2006,103 (14):5247-5248.
  • 10Sweeney WE Jr,Hamahira K,Sweeney J,et al.Combination treatment of PKD utilizing dual inhibition of EGF-receptor activity and ligand bioavailability[J].Kidney Int,2003,64(10):1310-1319.

二级参考文献39

  • 1Pan J,Wang Q,Snell WJ.Cilium-generated signaling and cilia-related disorders.Lab Invest,2005,85:452-463.
  • 2Ibanez-Tallon I,Heintz N,Omran H.To beat or not to beat:roles of cilia in development and disease.Hum Mol Genet,2003,12:R27-35.
  • 3Calvet JP.Ciliary signaling goes down the tubes.Nat Genet,2003,33:113-114.
  • 4Watnick T,Germino G.From cilia to cyst.Nat Genet,2003,34:355-356.
  • 5Zhang Q,Taulman PD,Yoder BK.Cystic kidney diseases:all roads lead to the cilium.Physiology (Bethesda),2004,19:225-230.
  • 6Pazour GJ.Intraflagellar transport and cilia-dependent renal disease:the ciliary hypothesis of polycystic kidney disease.J Am Soc Nephrol,2004,15:2528-2536.
  • 7Eley L,Yates LM,Goodship JA.Cilia and disease.Curr Opin Genet Dev,2005,15:308-314.
  • 8Scholey JM.Intraflagellar transport.Annu Rev Cell Dev Biol,2003,19:423-443.
  • 9Joly D,Hummel A,Ruello A,et al.Ciliary function of polycystins:a new model for cystogenesis.Nephrol Dial Transplant,2003,18:1689-1692.
  • 10Barr MM,Sternberg PW.A polycystic kidney-disease gene homologue required for male mating behaviour in C elegans.Nature,1999,401:386-389.

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二级引证文献27

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