肠运合剂治疗放射性肠炎42例疗效观察

Treatment of Radiation Enteritis by Changyun Mixture:A Clinical Observation of 42 Cases

目的:观察肠运合剂治疗放射性肠炎的临床疗效。方法:将80例患者随机分为2组,治疗组42例给予肠运合剂(组成:白术、葛根、白及、酸枣仁、合欢花、白芍、煅龙骨、茯苓、陈皮、桔梗、防风、大黄炭、甘草、木香)治疗;对照组38例口服复方谷氨酰胺肠溶胶囊,3周后对症状变化及疗效进行对比分析。结果:2组症状积分均较治疗前有不同程度下降(P< 0．05,P<0．01),但治疗组积分下降程度明显优于对照组(P<0．01)。治疗组与对照组痊愈率分别为76．19％、47．37％,总有效率分别为95．24％、68．43％,2组比较,差异均有非常显著性意义(P<0．01)。3月后复发率治疗组为9．38％、对照组为44．44％,2组比较,差异有非常显著性意义(P<0．01)。结论:肠运合剂治疗放射性肠炎临床疗效显著。

Objective: To observe the clinical effect of Changyun mixture (CM,肠运合剂) for radiation enteritis. Methods: 80 cases were allocated to 2 groups randomly, the treatment group (42 cases) was treated by CM: the control group (38 cases) by oral use of compound glutamine enteric solubility capsule, after 3 months of treatment, the changes of symptoms and curative effects were analysed. Results: The scoring of symptoms were decreased in different degree than that before treatment in both groups ( P < 0. 05, P < 0. 01), but the treatment group was markedly super than that of control group (P< 0.01), the cured rate was 76. 19% and 47. 37% , and the total effective rate was 95. 24% and 68. 43% in treatment group and control group respectively (P < 0. 01). After 3 months, the relapse rate was 9. 38% and 44. 44% in treatment group and control group respectively ( P < 0. 01). Conclusion: CM possesses markedly curative rate and low relapse rate for radiation enteritis.