期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

大鼠体外循环后肝损害与生长激素及其结合蛋白变化的关系及意义 被引量：1

原文传递
导出
摘要 肝脏是生长激素（GH）／胰岛素样生长因子-I（IGF-I）轴的中心器官，体外循环（CPB）时是否存在GH分泌不足及GH抵抗报道尚少。我们通过建立大鼠CPB模型，观察CPB围术期肝损害与GH-IGF-I轴的变化的关系。
作者 安永 肖颖彬
机构地区 第三军医大学新桥医院全军心血管外科中心
出处 《中华实验外科杂志》 CAS CSCD 北大核心 2007年第1期109-109,共1页 Chinese Journal of Experimental Surgery
关键词 体外循环后 生长激素 肝损害 GH-IGF-I轴 蛋白变化 大鼠 胰岛素样生长因子 CPB
分类号 R686 [医药卫生—骨科学]
  • 相关文献

参考文献4

  • 1Doguet F,Litzler PY,Tamion F,et al.Changes in mesenteric vascular reactivity and inflammatory response after cardiopulmonary bypass in a rat model.Ann Thorac surg,2004,77:2130-2137.
  • 2Massa GN,Mulumba J,Ketelslegers M,et al.Initial characterization and sexul dimorphism of serum growth hormone-binding protein in adult rat.Endocrinology,1990,126:1976-1980.
  • 3李井野,刘金钢,王勇,余云.生长激素对梗阻性黄疸血白细胞介素-2及其受体的影响[J].中华实验外科杂志,2005,22(9):1136-1136. 被引量：4
  • 4Fukushima R,Saito H,Inoue T,et al.Prophylactic treatment with growth hormone and insulin-like growth factor Ⅰ improve systemic bacterial clearance and survival in a murine model of burn-induced gut-derived sepsis.Burns,1999,25:425-430.

二级参考文献2

共引文献3

同被引文献29

  • 1安永,肖颖彬.大鼠体外循环后肝功能障碍与生长激素抵抗的关系[J].中国全科医学,2007,10(10):798-801. 被引量：1
  • 2Rau S, Kohn B, Richter C, Fenske N, Küchenhoff H, Hartmann K, H?rtle S, Kaspers B, Hirschberger J. Plasma interleukin-6 response is predictive for severity and mortality in canine systemic inflammatory response syndrome and sepsis. Vet Clin Pathol 2007; 36: 253-260.
  • 3Sánchez-Conde P, Rodríguez-López JM, Nicolás JL, Lozano FS, García-Criado FJ, Cascajo C, González-Sarmiento R, Muriel C. The comparative abilities of propofol and sevoflurane to modulate inflammation and oxidative stress in the kidney after aortic cross-clamping. Anesth Analg 2008; 106: 371-38, table of contents.
  • 4Copple IM, Goldring CE, Kitteringham NR, Park BK. The Nrf2-Keap1 defence pathway: role in protection against drug-induced toxicity. Toxicology 2008; 246: 24-33.
  • 5Gutteridge JM, Halliwell B. Comments on review of Free Radicals in Biology and Medicine, second edition, by Barry Halliwell and John M. C. Gutteridge. Free Radic Biol Med 1992; 12: 93-95.
  • 6Kwak MK, Cho JM, Huang B, Shin S, Kensler TW. Role of increased expression of the proteasome in the protective effects of sulforaphane against hydrogen peroxide-mediated cytotoxicity in murine neuroblastoma cells. Free Radic Biol Med 2007; 43: 809-817.
  • 7Maher JM, Dieter MZ, Aleksunes LM, Slitt AL, Guo G, Tanaka Y, Scheffer GL, Chan JY, Manautou JE, Chen Y, Dalton TP, Yamamoto M, Klaassen CD. Oxidative and electrophilic stress induces multidrug resistance-associated protein transporters via the nuclear factor-E2-related factor-2 transcriptional pathway. Hepatology 2007; 46: 1597-1610.
  • 8Maher JM, Aleksunes LM, Dieter MZ, Tanaka Y, Peters JM, Manautou JE, Klaassen CD. Nrf2- and PPAR alpha-mediated regulation of hepatic Mrp transporters after exposure to perfluorooctanoic acid and perfluorodecanoic acid. Toxicol Sci 2008; 106: 319-328.
  • 9Jain AK, Mahajan S, Jaiswal AK. Phosphorylation and dephosphorylation of tyrosine 141 regulate stability and degradation of INrf2: a novel mechanism in Nrf2 activation. J Biol Chem 2008; 283: 17712-17720.
  • 10Niture SK, Jaiswal AK. Prothymosin-alpha mediates nuclear import of the INrf2/Cul3 Rbx1 complex to degrade nuclear Nrf2. J Biol Chem 2009; 284: 13856-13868.

引证文献1

二级引证文献5

中华实验外科杂志
2007年 第1期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部