期刊文献+

肠道淋巴系统在多器官功能障碍综合征中的作用 被引量:2

下载PDF
导出
摘要 近20年,人们对肠道在脓毒症、感染、多器官功能障碍综合征(MODS)发病机制中的作用已经有了相当的认识。近年来,重症加强治疗病房(ICU)对肠道功能的评估局限在监测胃肠pH值和肠道的运动能力。这种方法反映了临床上的推测:如果除外应激性胃肠道出血,正常的胃肠道运动就等同于正常的肠道功能。按这种理论,肠道仅仅是一个把吸收的营养输送到机体全身的工厂。现在人们认识到,消化道不是一个被动的器官,胃肠道功能障碍不仅仅局限于上消化道出血。目前认为,肠道及其内容物,包括细菌、细菌产物都可以影响到患者的临床预后;肠道除了具有以往认识的营养吸收功能外,还具有重要的免疫、内分泌和屏障功能。
出处 《中国危重病急救医学》 CAS CSCD 北大核心 2007年第1期59-61,共3页 Chinese Critical Care Medicine
  • 相关文献

参考文献22

  • 1Deitch E A.Multiple organ failure.Pathophysiology and potential future therapy[J].Ann Surg,1992,216(2):117-134.
  • 2Woodcock N P,Sudheer V,El-Barghouti N,et al.Bacterial translocation in patients undergoing abdominal aortic aneurysm repair[J].Br J Surg,2000,87(4):439-442.
  • 3MacFie J,O'Boyle C,Mitchell C J,et al.Gut origin of sepsis:a prospective study investigating associations between bacterial translocation,gastric microflora,and septic morbidity[J].Gut,1999,45(2):223-228.
  • 4Moore F A,Moore E E,Poggetti R,et al.Gut bacterial translocation via the portal vein:a clinical perspective with major torso trauma[J].J Trauma,1991,31(5):629-636.
  • 5D'Amico R,Pifferi S,Leonetti C,et al.Effectiveness of antibiotic prophylaxis in critically ill adult patients:systematic review of randomised controlled trials[J].BMJ,1998,316(7140):1275-1285.
  • 6Welborn M B,Oldenburg H S,Hess P J,et al.The relationship between visceral ischemia,proinflammatory cytokines,and organ injury in patients undergoing thoracoabdominal aortic aneurysm repair[J].Crit Care Med,2000,28(9):3191-3197.
  • 7Biffl W L,Moore E E.Splanchnic ischaemia/reperfusion and multiple organ failure[J].Br J Anaesth,1996,77(1):59-70.
  • 8Magnotti L J,Upperman J S,Xu D Z,et al.Gut-derived mesenteric lymph but not portal blood increases endothelial cell permeability and promotes lung injury after hemorrhagic shock[J].Ann Surg,1998,228(4):518-527.
  • 9Zallen G,Moore E E,Johnson J L,et al.Posthemorrhagic shock mesenteric lymph primes circulating neutrophils and provokes lung injury[J].J Surg Res,1999,83(2):83-88.
  • 10Deitch E A,Adams C,Lu Q,et al.A time course study of the protective effect of mesenteric lymph duct ligation on hemorrhagic shock-induced pulmonary injury and the toxic effects of lymph from shocked rats on endothelial cell monolayer permeability[J].Surgery,2001,129(1):39-47.

二级参考文献43

共引文献94

同被引文献23

引证文献2

二级引证文献41

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部