肾移植患者血清垂体-性腺激素、微量元素的测定及其性功能的研究

Measurements of serum pituitary-gonadal hormones and trace elements and investigation of sexual function in renal transplant recipients

测定了24例肾移植患者移植前、移植术后1～4个月血清垂体-性腺激素及血清微量元素的浓度,在此基础上,又对肾移植术后存活3年以上的已婚患者100例进行了性功能及生育能力的调查。结果表明,慢性肾功能衰竭患者常伴有下丘脑-垂体-性腺轴功能和机体内环境的紊乱,而血液透析不能改善这种异常。肾移植术后3个月患者的血清垂体-性腺激素及微量元素的异常多能得到纠正。移植术后患者性功能恢复的比例较高,达60.94%。我们认为肾移植患者恢复性生活的时间应在移植术后肾功能正常达3个月以上。妊娠易导致移植肾功能恶化及诱发排斥,一旦妊娠,必须严密监护。

The serum pituitary-gonadal hormones and trace elements were measured in 24 re- nal transplant cases both pretransplantly and 1～4 monthes posttransplantly.Based on this the re- habilitation of sexual function and fertility of 100 married kidney transplant recipients who had a normal functioning graft for at least 3 years were investigated.The results indicated that chronic renal failure was associated with complex disturbance of the hypothalamic-pituitary-gonadal axis, and successful renal transplantation could ameliorate this disturbance.The rehabilitation rate of the sexual function and fertility was 60.94%3 monthes after transplantation.Pregnancy could lead to deterioration of graft function and need close monitoring.