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TEM型β内酰胺酶的特征及其研究进展 被引量：4

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摘要 TEM型B内酰胺酶是目前世界上最为流行且种类最多的质粒编码丝氨酸蛋白酶，其中TEM-1是革兰阴性菌中最常见的B内酰胺酶，约90％对青霉素耐药的大肠埃希菌都产生TEM-1。除肠杆菌科菌外，近年来TEM-10在葡萄牙的克吕沃尔菌属、TEM-21在美国的绿脓假单胞菌、TEM-52在韩国的宋内志贺菌HJ、TEM-52、TEM-63、TEM-131在韩国和南非的非伤寒沙门菌中也有报道。截止2006年1月30日，Bush和Jacoby在Lahey网站（http：／／www.lahy．org／studies／webt．htm）上已公布了150种TEM型β内酰胺酶，其中2000-2006年就发现了70多种。
作者 王瑶 徐英春 陈民钧
机构地区 中国医学科学院中国协和医科大学北京协和医院检验科
出处 《中华检验医学杂志》 CAS CSCD 北大核心 2007年第2期224-226,共3页 Chinese Journal of Laboratory Medicine
关键词 Β内酰胺酶 TEM型 TEM-1 丝氨酸蛋白酶 绿脓假单胞菌 非伤寒沙门菌 革兰阴性菌 大肠埃希菌
分类号 R515 [医药卫生—内科学]
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参考文献21

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二级参考文献23

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共引文献188

同被引文献33

  • 1季淑娟,顾怡明,谭文涛,王丹丹,冯羡菊,周志慧,俞云松,陈亚岗,李兰娟.中国部分地区大肠埃希菌和肺炎克雷伯菌超广谱β内酰胺酶基因型研究[J].中华检验医学杂志,2004,27(9):590-593. 被引量：172
  • 2陈晶,孙自镛.非伤寒沙门菌耐喹诺酮类药物机制的研究进展[J].国外医药（抗生素分册）,2005,26(6):271-274. 被引量：5
  • 3胡大春,邵剑春,杨绍敏,周玲,李超,刘德华.肺炎克雷伯菌超广谱β-内酰胺酶基因型研究[J].中国抗生素杂志,2006,31(1):19-22. 被引量：26
  • 4李金钟（综述）,刘利平（审校）.CTX-M型β-内酰胺酶的研究进展[J].国际检验医学杂志,2007,28(6):543-545. 被引量：13
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引证文献4

二级引证文献27

中华检验医学杂志
2007年 第2期

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