对叔丁基杯[8]芳烃醚类衍生物的合成

Synthesis of t-Butylcalix[8]arene Ether Derivatives

以对叔丁基苯酚和甲醛为原料,在碱催化下,采用一步法合成了对叔丁基杯[8]芳烃(1)。对1的下缘酚羟基改性,用碘甲烷、碘乙烷、正溴丙烷、正溴丁烷为烷基化试剂,在氢化钠作用下,制备了一系列全O-烷基化的杯[8]芳烃醚衍生物,其结构经1HNMR和IR表征。

t-Butylcalix [8] arene （1） was synthesized from p-t-butylphenol and formaldehyde by onepot reaction. The phenolic groups of 1 were modified using alkylating agents under Nail to obtain octaalkylethers（2a～2d） of t-butylcalix[8] arene. The structures of 2 were characterized by ^1H NMR and IR.