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Raman spectroscopy of Chinese human skin in vivo 被引量:2

Raman spectroscopy of Chinese human skin in vivo
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摘要 A novel and compact near-infrared (NIR) Raman system is developed using 785-nm diode laser, volumephase technology (VPT) holographic system, and NIR intensified charge-coupled device (CCD). Signal-tonoise ratio (SNR) and resolution are improved compared with ordinary acquisition method by a specially designed optical fiber detector and the spectrograph image aberration correction with a parabolic-line fiber array. In 1-5 s, Raman spectra of different parts of Chinese human skin are acquired. Autofluorescence is subtracted from the raw spectrum by polynomial fitting and skin Raman spectrum is then smoothed for further analysis. A novel and compact near-infrared (NIR) Raman system is developed using 785-nm diode laser, volumephase technology (VPT) holographic system, and NIR intensified charge-coupled device (CCD). Signal-tonoise ratio (SNR) and resolution are improved compared with ordinary acquisition method by a specially designed optical fiber detector and the spectrograph image aberration correction with a parabolic-line fiber array. In 1-5 s, Raman spectra of different parts of Chinese human skin are acquired. Autofluorescence is subtracted from the raw spectrum by polynomial fitting and skin Raman spectrum is then smoothed for further analysis.
出处 《Chinese Optics Letters》 SCIE EI CAS CSCD 2007年第2期105-107,共3页 中国光学快报(英文版)
基金 This work was supported by the Key Project of Ministry of Education (No. 205081) the Project of Fujian Province (No. 20051009, JA04168) the Project of Fujian Development and Reform Commission (No.2005-847).
关键词 ABERRATIONS Charge coupled devices Detectors Optical fibers POLYNOMIALS Raman scattering Semiconductor lasers Signal to noise ratio SKIN Aberrations Charge coupled devices Detectors Optical fibers Polynomials Raman scattering Semiconductor lasers Signal to noise ratio Skin
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