早期新生儿尿系列微量蛋白的排泌量及意义

Detection of uric systematic trace amount proteins in neonatal infants and its significance

作者对９０例新生儿进行尿系列微量蛋白的测定，包括：ＲＢＰ，Ａｌｂ，ＩｇＧ和ＮＡＧ。新生儿分为早产儿组和足月儿组。二组间进行对照，并分别与成人组对照。结果显示：新生儿各组的均值明显高于成人正常值（Ｐ＜０．０１）。早产儿又明显高于足月儿（Ｐ＜０．０１）。该结果说明，肾脏的发育是随着胎龄的增大而逐渐成熟的。作为一种简便而敏感的方法，该项检查可应用于诸如筛查药源性肾脏损害或新生儿窒息的评估等。

we detected uric systematic trace amount proteins of 90 neonatal infant,which include albumin,immune globulin G(IgG),N-acety 1-β-D-glucosaminidase(NAG)and retinol-binding protein(RBP).The newborn infants were divided into premature infant and full term infant groups.Which were compared with a group of healthy adule.The experiments revealed:the mean of uric systematic trace amount proteins in each newborn infant group is higher than that of adult(P<0.01),and in premature infant is higher than full term infants(P<0.01).The resule suggest that the large of gestational age,the mature of renal development.As a simple and sensitive method,this detection can be used in many ways.For example screening for renal damage by drug or evaluation of asphyxia neonatorum.