二氢麦角毒治疗Alzheimer病的临床观察

An open study of dihydro-ergotoxine treatment in Alzheimers disease

本研究应用二氢麦角毒治疗１５例男性Ａｌｚｈｅｉｍｅｒ病病人６个月，采用ＭＭＳＥ和ＭＯＳＥＳ评定精神症状的疗效，ＴＣＤ观察颅内血液循环状况。本研究显示：二氢麦角毒治疗Ａｌｚｈｅｉｍｅｒ病病人的精神症状总有效率为７３．３％。１０例（６６．７％）病人颅内血液循环改善，其中９例（９／１０）精神症状好转。说明改善病人颅内血液循环，可使精神症状改善。

bjective:To study the effect of dihydro-ergotoxine treatment on Alzheimers disease.Method:15 patients with Alzheimers disease were treated with dihydro-ergotoxine for 6 months.The MMSE and MOSES were used to evaluate psychiatric symptoms and the TCD was used to measure intracranial blood circulation.Results:73 3% of patients improved in terms of their psychiatric symptoms.Blood circulation was enhanced in 10(66 7%) patients.Discussion:Dihydro-ergotoxine may alleviate Alzheimers disease by enhancing intracranial blood circulation.