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前列腺特异性抗原及其分子亚型检测的临床意义

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摘要 1979年Wang首次成功地从前列腺组织中分离和提纯出分子量为35000的糖蛋白并命名为前列腺特异性抗原(prostate specific antigen,PSA),PSA已成为临床上最常用的诊断前列腺癌(prostate cancer)的肿瘤标记物。随着研究的不断深入。人们发现PSA还存在多种分子亚型。而且这些分子亚型对于前列腺癌的早期诊断更为敏感和特异。从而为前列腺癌和前列腺良性增生(benign prostic hyperplasia)的鉴别以及前列腺癌的早期诊断提供了新的手段。
出处 《实用医学杂志》 CAS 2007年第4期598-599,共2页 The Journal of Practical Medicine
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参考文献15

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