甲氯芬酯治疗急性脑梗死疗效观察

Effects of Meclofenoxate on Acute Cerebral Infarction

目的观察甲氯芬酯诊治急性脑梗死的疗效。方法急性脑梗死病例共计156例,随机分为2组,治疗组在对照组治疗方案(血栓通注射液等)的基础上加用甲氯芬酯一日1次0.3g静滴,14天为一个疗程。结果治疗组患者临床症状和体征消失或有明显改善,与对照组相比,差异显著。结论甲氯芬酯对于急性脑梗死患者的临床症状和体征的改善是有效的,并且安全性好,不良反应少。

Objective To observe the effects of meclofenoxate on acute cerebral infarction. Methods 156 patiants with acute cerebral infarction were randomly divided into two groups. The test group（n=78） was administrated the same treatment compare to the other 78 patiens in the control group besides receiving meclofenoxate （0.3g qd ivgtt） for 14days. Result Both 30 patients in test group and 23 patients in control group had got obvious improvment. The total effective ratio of the test group was higher than that of the control group（88.46% vs 73.07%, P〈0.05） significantly. Conclusion Meclofenoxate can be used in the treatment of acute cerebral infarction receiving satisfactory effection and less adverse affection.