新生儿高胆红素血症的听觉脑干诱发反应及诱发性耳声发射的临床意义

CLINICAL STUDY OF AUDITORY BRAINSTEM EVOKED RESPONSE (ABER) AND EVOKED OTOACOUSTIC EMISSIONS (EOAEs) IN NEONATAL HYPERBILIRUBINEMIA

本文对3O例（60耳）新生儿高胆红素血症及22例（44耳）正常新生儿为对照进行听觉脑干诱发反应（ABR）及诱发性耳声发射（EOAES）检测。30例（60耳）高胆病人异常耳数分别为41．67％，33.33％；正常对照组检测结果异常耳数分别为0，6．82％。同时发现随着血清总胆红素浓度升高，异常耳数增加，并证实约有1／3病人有耳蜗外毛细胞受损。提示新生儿高胆病人听觉系统损害发病率较高。以上两种方法检测是一种无创伤性，并能客观地反映听力及脑子功能、耳蜗外毛细胞受损。可通过以上检测更准确地确定受损部住，以便及时治疗减少后遗症发生。

Thirty cases (60ears) of neonatal hyperbilirubinemia and 22 cases (44 ears) of normal newborn infantswere tested by Auditory Brainstem Evoked Response (ABER) and Evoked otoacoustic Emissions (EOAEs).The percentage of abnormal ears in the 30 patients were 41. 67% (ABER) and 33- 33% (EOAEs) while thepercenage of abnormal ears in the normal neonates were 1% and 6. 8% respectirely. Meanwhile we foundthat the higher concentrations of bilirubin in serum the more abnormal ears in patients. The acoustie haircells were damaged in one-third of the patients. These indicated that neonates suffered from hyperbilirubinemia had a bigh rate of damage in anditory system