超声检测小叶间血管对慢性肾脏病诊断价值探讨

Ultrasound evaluation of interlobular vessels in the diagnosis of chronic kidney disease

目的:探讨超声eflow成像检测小叶间血管在慢性肾脏病(CKD)诊断及分期中的价值。方法:常规超声探查43例健康对照者及57例CKD不同分期患者肾脏,测量肾脏各段动脉阻力指数(RI)。超声eflow成像显示小叶间血管,根据其血流信号分布范围进行分型。结果:各期CKD患者弓形动脉、小叶间动脉RI均与健康对照组有显著性差异(P<0.05);CKD患者轻度肾损害小叶间动脉RI较中重度肾损害有显著性差异(P<0.05);应用eflow显像对小叶间血管的分型分析表明CKD各期的小叶间血管较健康对照组均有减少,差异有显著性意义,且轻度肾损害小叶间血管较中重度肾损害丰富,差异有显著性意义。结论:超声eflow成像技术是一种准确评价CKD血流变化的方法。

Objective： To evaluate interlobular vessels with ultrasound in the diagnosis of chronic kidney diseases（CKD）. Methods： A total of 57 CKD patients at different stages and 43 healthy adults served as control were enrolled in the study. Several dimensions of kidneys and resistance index（RI） of arteries were measured. Interlobular arteries were studied with eflow, and all the kidneys were classified into five types according to the ratio of interlobular artery to cortex. Results： When arcuate and interlobular arteries were detected, RI of CKD patients in each stage increased significantly compared with the control group, and RI of interlobular arteries of mild renal dysfunction patients were different from those of moderate and severe renal dysfunction patients significantly. The eflow types of CKD patients in each stage were different with the control group significantly, and the eflow of mild renal dysfunction was different from those of moderate and severe renal dysfunction significantly. Conclusions： Eflow, a new method of blood flow, can assess renal function and differentiate mild renal dysfunction from moderate and severe renal dysfunction.