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多发性骨髓瘤的外科治疗 被引量:9

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摘要 目的探讨多发性骨髓瘤外科治疗的手术指征、目的、方式和效果。方法回顾性分析17例孤立性骨髓瘤和多发性骨髓瘤患者的临床特点、手术指征、目的、方式以及治疗效果。手术病灶位于脊柱10例,肱骨干1例,股骨上端3例,股骨干2例,骨盆1例。术后评估了患者疼痛、神经功能损害以及生活质量情况。结果17例术后均随访6个月以上,疼痛均得到明显缓解或消失,神经系统症状亦得到明显改善,生活质量有明显提高,对比术前和术后1个月及6个月患者生活质量指数,差异有显著性(P<0.01)。术中及术后无严重并发症发生。在随访期间,2例局部复发,1例孤立性骨髓瘤出现其它部位病变。结论手术治疗能够有效减轻或缓解疼痛,稳定和重建脊柱,恢复肢体活动,维持和改善神经功能,进而提高患者的生活质量。
出处 《实用肿瘤杂志》 CAS 2007年第1期40-44,共5页 Journal of Practical Oncology
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