新生儿惊厥病因及治疗探讨（附155例临床报告）

Etiologic and treatment on neonatal seizures(Attaching the clinical analysis of 155 cases)

本组收集新生儿惊厥１５５例，占同期新生儿重症监护病房收治９１６例患儿的１６．４５％，其中治愈１２４例，好转３例，自动出院１７例，有明显后遗症１７例，死亡１１例，死亡率为７．０９％。资料对新生儿病因及治疗进行分析、探讨，其结果：窒息引起脑损害增加，足月儿惊厥发病较早产儿增加。病因以缺血缺氧性脑病和／或颅内出血，低钙血症、重症感染为主，非感染性疾病占９０．３％，因此表明要减少新生儿惊厥的发病率及死亡率，主要在于减少窒息，而对于窒息应防重于治。文中讨论了防治的经验。

cases of neonatal seizures were admitted.The incidence rate was 1.45% among totally 916 cases in NICU during the same period.There were 124 cases being cured.3 cases getting better,17 cases being active discharge,and 11 cases being died.There were 17 cases had been sequelaed.There rnaterials show:Asphysia have made increating in brain's injury.The paroxysm of mature infants seizures was inereater than premature infants’The injor causes of seizurs were HIE/or intractanial hemorrhage,Hypocalcemia and serious infections,In order to decrease the morbidity and mortality of neonatal seizures,we must decrease asphyxia first.Treatrnent on asphyxia was more important than prevention.For clinical analysis using phenobartital loading dose of 10-30mg/kg was recommended for contralling seizures.Treatment on stopping seizures soon.We could use drugs for antioxygenic free redicals and use to improve brain cells'metabolites at early time,Then that could maked significantly results in minimizing brain anoxemia,encephaledema,and decreasing symptom and sequela of nervous system also.