含羟基醚链桥联的双水杨醛亚胺席夫碱的合成

Synthesis and Characterization of Schiff Base of Acyclic Crown of Hydroxyl-bearing Group

报道以水杨醛、环氧氯丙烷为原料,合成中间体1,3-双(2-甲酰基苯氧基)-2-丙醇,然后中间体再与邻氨基对甲苯酚合成含羟基醚链桥联的双水杨醛亚胺新型席夫碱,并探讨了合成中间体的最佳合成条件,在水杨醛与环氧氯丙烷物质的量之比为2.5∶1时、溶液的pH为8、反应温度为50-60℃、反应达6 h的产率达到50%;通常产物的合成pH值控制在7-8之间就可以得到较高的产率。中间体和产物用元素分析、紫外光谱和红外光谱(KBr压片)进行了表征。

Novel Schiff base of acyclic crown of hydroxyl-bearing group was synthesized by the condensation of an intermediate, 1,3-bis（2-formylphenoxy）-2-propanol, and o-amino-p-methylphenol. The favorable reaction conditions of preparing the intermediate were found as follows： the pH of reacting solution was from 7 to 8, the reacting time was about 6 h, the reacting temperature was 50 - 60℃, and the tool ratio of salicylaldehyde to 1-chloro-2,3-epoxypropane was 2.5 to 1. The intermediate yield was 50%＇. The intermediate and the novel Schiff base were characterized by elemental, analysis UV and IR spectroscopy.