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急性冠状动脉综合征患者体内T细胞亚群的变化及活化 被引量：1

Activation and Changing of Tlymphocytes Composition in Acute Coronary Syndromes
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摘要 目的研究T淋巴细胞是否参与了急性冠脉综合征(ACS)相关的炎症反应。方法采用流式细胞分析仪分析64例ACS患者和66例健康者循环T淋巴细胞亚群和T细胞激活标志物HLA-DR抗原的表达。结果ACS患者HLA-DR阳性的淋巴细胞数量显著高于健康者。结论ACS患者循环CD4+T淋巴细胞被激活,T细胞参与了ACS的发生。 Objective To investigate whether circulating T lymphocytes took part in the Inflammatory reaction which related to acute coronary syndromes. Methods 64 patients with acute coronary syndromes, and 66 healthy subjects were studied. CD4^＋ T lymphocytes and HLA - DR were investigated by flow cytometric analysis. Results The results demonstrated that the number of CD4^＋ T cells and CD^＋ DR^＋ cells in patients with acute coronary syndromes were higher（ P 〈 0.05） than those in control subjects. Conclusion These results suggestthat CD4^＋T cell were activated, and circulating T lymphocytes may play an important role in the development of acute coronary syndromes.
作者 崔颖 李璐璐 姜明
机构地区 哈尔滨医科大学第二临床医学院检验中心
出处 《黑龙江医学》 2007年第2期91-92,共2页 Heilongjiang Medical Journal
关键词 急性冠状动脉综合征 T淋巴细胞 HLA—DR抗原 Acute coronary syndromes CD4^＋T lymphocytes HLA-DR
分类号 R541.4 [医药卫生—心血管疾病]
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参考文献3

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同被引文献11

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  • 10钟文亮,李志梁,刘映峰,付强,菅颖.外周血CD4^+CD28^+T淋巴细胞数量与阿托伐他汀对急性冠脉综合征患者干预的相关性[J].中国组织工程研究与临床康复,2007,11(46):9297-9300. 被引量：3

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黑龙江医学
2007年 第2期

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