北京地区反流性食管炎患者幽门螺杆菌感染率调查

An Investigation about the Ratio of the Helicobacter Pylori Infection of Patients with Reflux Esophagitis in Beijing

目的调查近3年来北京地区反流性食管炎患者幽门螺杆菌(Hp)感染率,分析目前反流性食管炎与Hp感染的相关性。方法选择反流性食管炎患者119例和正常对照组121例,以快速尿素酶试验及13C-尿素呼气试验检测Hp感染。结果反流性食管炎患者Hp感染率(26.89%),显著低于对照组(42.15%),P<0.05。结论Hp可能在反流性食管炎的发病中起到保护作用。

Objective To investigate the ratio of the helicobecter pylori（Hp） infection of patients with reflux esophagitis（RE） in Beijing and study the relationship between RE and Hp. Methods 119 patients with RE and 121 controls were enrolled for the study. 3 biopsy specimens obtained from the gastric antrum for rapid urease test,at the same time ^13C-rapid urea breath test（13C-UBT） was used for everyone,Hp infection was affirmed when the two tests were positive. Results The ratio of the Hp infection found in the patients with RE was 26. 89% ,which was lower than the ratio of the controls,42. 15%, P 〈 0. 05. Conclusion Hp may give some protection to RE.