痰热清注射液联合抗生素治疗脑梗死合并肺炎的临床研究

Clinical Research on Treatment Effect of Tanreqing Injection Combining with Antibiotics for Cerebral Infarction Patients with Pneumonia

目的探讨痰热清注射液联合抗生素治疗脑梗死合并肺炎的疗效。方法将84例脑梗死合并肺炎患者随机分为两组,对照组41例患者常规使用抗生素及支持对症治疗,治疗组43例患者在此基础上同时给予痰热清注射液20ml加入5%葡萄糖溶液或0.9%氯化钠溶液500ml中静脉滴注,1次/d,疗程均为2周。观察两组患者的临床疗效、WBC、C-反应蛋白(CRP)、体温恢复正常的时间及住院天数。结果两组患者临床疗效间差异有显著性意义(P<0.05);两组患者治疗前、后症状积分间差异均有显著性意义(P<0.05),且治疗后两组患者症状、体征积分间差异亦有显著性意义(P<0.05)。两组患者治疗前、后WBC、中性粒细胞比例、CRP间差异均有显著性意义(P<0.05),且两组患者体温恢复正常时间、住院天数间差异亦均有显著性意义(P<0.05)。结论痰热清注射液联合抗生素治疗脑梗死合并肺炎的临床疗效优于单纯抗生素治疗。

Objective To study the treatment effect of Taming injection with antibiotics for cerebral infarction patients with pneumonia. Methods 84 cerebral infarction patients with pneumonia were randomly divided into two groups, a treatment group of 43 cases and a control group of 41cases. The patients of control group were treated with antibiotics as well as support therapy for two weeks. The patients of another group were treated with Tanreqing injection （20ml one day） besides for those therapies as well. The result of these therapies, blood white cell, C reaction protein （CRP）, days of turning to normal temperature and hospital stay of patients were observed. Results The rate of efficiency in the treatment group （ 88. 4% ） was superior to that in the control group （70. 7 % ） （ P 〈 0. 05 ）. There was also a significant difference in CRP, days of turning to normal temperature and hospital stay of patients between the two groups （ P 〈 0. 05）. The side effect was low in both groups. Conclusion The treatment effect of Tanreqing injection with antibiotics for cerebral infarction patients with pneumonia is better than that of using antibiotics only.