药物引起的血小板减少307例分析

Analysis of 307 Cases of Drug-induce Thrombocytopenia

目的:探讨药物引起血小板减少的特点及一般规律。方法:对1996年1月—2006年6月国内报道的药物引起的血小板减少307例进行统计、分析。结果:药物引起的血小板减少共涉及13类药物,以抗感染药物、中药制剂和菌苗制剂为主,其中以穿琥宁注射液最多,有72例(23.45%)。结论:掌握引起血小板减少的药物分布规律,确保用药安全。

OBJECTIVE To discuss the general regularity and characteristics of drug - induced thrombocytopenia. METHODS 307 cases of drug - induced thrombocytopenia reported in internal medical journals published from Jan. 1995 to Jun. 2006 were collected and analyzed. RESULTS The drugs induced thromboeytopenia were chiefly Anti - infectives drugs0 Chinese material medicament preparation and Bacterial vaccines, The Andrographolide injection induced cases was reported mostly,72 cases 23.45 %. CONCLUSION It is important to handle the distributive axiom of drug induced thromboeytopenia for the safety of medication.