大型不染色细胞在上呼吸道感染中的临床意义

Clinical significance of large unstained cells in upper respiratory infection

目的：探讨大型不染色细胞（large unstained cells，Luc）的正常参考值及在上呼吸道感染中的应用。方法：统计分析2003年9月～2004年3月我院健康体检者922例血常规中的LUC，建立LUC的参考值；统计分析2004年11月到2005年5月我院住院或门诊上呼吸道感染者2113例及同年龄儿童对照组583例血常规中的LUC。结果：LUC的正常参考值为＜3．76％；小儿上呼吸道感染者LUC值较高，与正常人比较有统计学意义（P＜0．01）．其余病例与正常人LUC比较没有统计学意义（P＞0．05）；儿童组中年龄大于11岁的LUC％与对照组比较没有统计学意义（P＞0．05），而其他组与对照组比较均有统计学意义（P＜0．01）；儿童组中年龄大于11岁的LUC％大于4．5％的百分比与对照组比较没有统计学意义（P＞0．05），而其他组与对照组比较均有统计学意义（P＜0．01）。结论：LUC在不同的年龄组中存在明显的差异，小儿明显高于成人。

Objectlve：To discuss the normal reference value of LUC （large unstained cells） and its clinical application in the upper respiratory infection. Methods： the LUC data of 922 routine blood tests was collected from those practicing health examination from September 2003 to March 2004, and constituted the normative value. We analyze the LUC statistically of 2 113 inpatients or outpatients and 583 controls with routine blood tests from November 2004 to May 2005. Results：The normal reference value of LUC was less than 3.76% ; And the value of children with upper respiratory infection was higher than that of normal ones, which had significant difference compared with the normal reference value （P 〈0.01 ）. While the others had no significant differences （P 〉 0.05） ; Among the children＇s group LUC% of those aging above 11 years old had no significant differences compared with the reference groups （P 〉 0.05 ）, but other classes in this group had significant differences （P 〈 0.01 ）. Also LUC% of those children older than 11 years old whose was higher than 4.5% had no significant differences compared with the reference groups （P 〉 0.05）, whereas the other classes had significant differences （ P 〈 0.01 ）. Conclusion： There is remarkable difference in LUC among different age class, and children＇ s LUC is distinctly higher than that of the adults.