用SPECT研究针刺对脑血流量和脑功能的影响

Study on Effects of Acupuncture on Cerebral Blood Flow and Brain Function by SPECT

用ＳＰＥＣＴ和９９ｍＴｃ－ＥＣＤ研究了６３例（１８９人次）正常人和缺血性脑血管病病人针刺前、留针和电针时ｒＣＢＦ和脑功能活动的变化。ＳＰＥＣＴ显示，针刺一侧肢体穴位时，以对侧大脑皮质、对侧丘脑、同侧基底节和双侧小脑皮质ｒＣＢＦ和脑功能活动增高变化为主。缺血性脑血管病人比正常人反应更敏感。提示，针刺的效应发挥依赖于中枢神经系统的调节，可能是通过特异感觉和非特异感觉传入系统，同时亦有锥体外系、小脑和交感系统参与实现的。

Changes of rCBF and brain function before and during acupuncture, and electroacupuncture were investigated by SPECT and brain perfusion agent 99mTcECD in 63 normal volunteers and ischemic cerebrovascular patients. SPECT image showed that rCBF and brain function increased in the contralateral cerebral contex,the contralateral thalamus,the ipsilateral basal ganglia and bilateral cerebellum during acupuncture at points of extremities on one side and ischemic cerebrovascular patients. In addition,rCBF and brain function were improved in focal areas. The results suggest that acupuncture effets depend on regulation of the central nervous system, and specific and nonspecific sensory afferent nerve systems, the extrapyramidal system,the cerebellum and the sympathetic system are possibly involved.