期刊文献+

感染和炎症对脂代谢的影响

下载PDF
导出
摘要 感染和炎症引起的急性期反应可以导致多种脂质和脂蛋白改变。产生这些变化的分子机制与许多核受体有关,如过氧化物酶增生物激活受体(PPAR)、肝X受体(LXR)、核黄素X受体(RXR)、法尼醇X受体(FXR)。近年来,人们对感染和炎症引起的脂代谢及相关核受体的变化进行了大量研究,现对其进行一简要回顾。
出处 《国际检验医学杂志》 CAS 2007年第2期136-138,共3页 International Journal of Laboratory Medicine
基金 国家自然科学基金资助重点项目(No.30530360)
  • 相关文献

参考文献16

  • 1Ohashi R, Mu H, Wang X, et al. Reverse cholesterol transport and cholesterol efflux in atherosclerosis [J]. QJM, 2005, 98(12):845-856.
  • 2Ory DS, Nuclear receptor signaling in the control of cholesterol homeostasis: have the orphans found a home[J]? Cire Res, 2004,95(7) : 660-670.
  • 3Lambert G, Amar MJ, Guo G, et al. The farnesoid X-receptor is an essential regulator of cholesterol homeostasis [J]. J Biol Chem, 2003, 278(4): 2563-2570.
  • 4Kim MS, Shigenaga J, Moser A, et al. Repression of farnesoid X receptor during the acute phase response [J]. J Biol Chem, 2003, 278(11) : 8988-8995.
  • 5Castrillo A, Joseph SB, Vaidya SA, et al. Crosstalk between LXR and toll-like receptor signaling mediates bacterial and viral antagonism of cholesterol metabolism[J]. Mol Cell, 2003, 12(4) : 805-816.
  • 6Feingold K, Kim MS, Shigenaga J, et al. Altered expression of nuclear hormone receptors and coactivators in mouse heart during the acute-phase response[J]. Am J Physiol Endocrinol Metab, 2004, 286(2): E201-E207.
  • 7Lee CH, Olson P, Evans RM. Minireview: lipid metabolism, metabolic diseases, and peroxisome proliferator-activated receptors [J]. Endocrinology, 2003, 144(6): 2201-2207.
  • 8Wang YX, Lee CH, Tiep S, et al. Peroxisome-proliferator-activated receptor delta activates fat metabolism to prevent obesity[J]. Cell, 2003, 113(2): 159-170.
  • 9Francis GA, Fayard E, Picard F, et al. Nuclear receptors and the control of metabolism[J]. Annu Rev Physiol, 2003, 65: 261-311.
  • 10Kitchens RL, Thompson PA. Impact of sepsis-induced changes in plasma on LPS interactions with monoeytes and plasma lipoproteins: roles of soluble CD14, LBP, and acute phase lipoproteins [J]. J Endotoxin Res, 2003, 9(2): 113-118.

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部