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糖尿病肾病患者C反应蛋白和脂蛋白(a)的变化及其相关性研究 被引量:2

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摘要 目的探 讨血清C反应蛋白(CRP)和脂蛋白(a)[Lp(a)]与糖尿病肾病(DN)的关系。方法 根据尿白蛋白排泄率(UAE)将112例2型糖尿病(DM)患者分为单纯糖尿病组(SDM组)、糖尿病肾病组(DN组),38例健康者作为健康对照组。分别测定各组血清CRP和Lp(a)的水平,并与健康对照组比较。结果 CRP、Lp(a)水平SDM组与健康对照组比较无统计学差异(P〉0.05),但DN组显著高于SDM组和健康对照组(P〈0.01)。CRP和Lp(a)分别与UAE星显著正相关(r=0.438、0.416,P〈0.01)。结论 DN患者血清CRP和Lp(a)水平随着UAE的增加而升高,两者之间关系密切,可能与DN的进展有关。
出处 《国际检验医学杂志》 CAS 2007年第2期162-163,共2页 International Journal of Laboratory Medicine
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