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血透患者血清瘦素水平与贫血的关系(附83例临床分析)

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摘要 目的:探讨血液透析(血透)患者血清瘦素水平以及瘦素与贫血的关系。方法:83例血透患者分为促红细胞生成素(EPO)治疗组及非EPO治疗组,28例未行血透治疗的慢性肾脏病患者及24例健康体检者为透析前及健康对照组。ELISA法测定血清瘦素水平,计算各组体重指数(BMI),测定血常规、血液生化、铁蛋白、转铁蛋白、C反应蛋白及甲状旁腺激素,用SPSS11.0统计软件进行统计分析。结果:血透患者血清瘦素水平高于透析前肾脏病患者及健康人,后二者之间血清瘦素水平无明显差异;女性血清瘦素水平高于男性患者;血透患者的血清瘦素水平与血红蛋白及转铁蛋白正相关(P<0.05)。结论:血透患者血清瘦素水平高于透析前的慢性肾脏病患者及健康成人,女性高于男性。血透患者的血清瘦素水平与患者的血清胆固醇水平、BMI以及血红蛋白正相关。透析治疗对血清瘦素无影响。血透患者血清瘦素水平的升高,不仅仅是GFR下降引起,也是对慢性肾衰竭时血红蛋白减少的一种代偿。
出处 《中国中西医结合肾病杂志》 2007年第2期104-105,共2页 Chinese Journal of Integrated Traditional and Western Nephrology
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参考文献9

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