摘要
目的探讨化学位移成像在MR引导下VX2兔行经皮穿刺乙酸化学消融的应用价值。方法制备18只肝VX2瘤兔,在1.5T磁共振扫描仪引导下,应用FRFSET2WI化学位移成像完成实验模型及经皮肝穿刺乙酸化学消融VX2瘤兔术中的扫描。结果50%乙酸注射的相关部位信号明显的增加。在对VX2瘤兔行经皮肝穿刺乙酸化学消融时,化学位移成像乙酸弥散范围(最大层面)与大体标本肿瘤的坏死范围(最大层面)存在显著的正相关性(r=0.936)。结论化学位移成像能够用于监控MR引导化学消融肝肿瘤时乙酸的分布。
Objective To study the application of chemical-shift MR imaging during percutaneous acetic acid chemical ablation procedures in rabbits bearing liver tumor. Methods VX2 tumors were carried out in 18 rabbits. Chemical-shift MR imaging was performed in phantom and VX2 tumors rabbits during percutaneous chemical ablation with FRFSE on a 1.5T MR scanner. Results Phantom data demonstrated focal increases in the observed signal in chemical-shift MR imaging that correlated well with the site of injection. The study in a hepatic VX2 tumor of rabbits revealed focal signal at the injection site. It was significant positive in the radiologic-pathologic correlation. Conclusion Chemical-shift MR imaging may be used to visualize the acetic acid distribution during percutaneous chemical ablation procedures.
出处
《中国医学影像技术》
CSCD
北大核心
2007年第1期5-8,共4页
Chinese Journal of Medical Imaging Technology
基金
国家"十五"科技攻关项目([2004]338号)
同济医院人才基金[2004(1)]基金资助。
关键词
化学位移
磁共振成像
乙酸
VX2肿瘤
Chemical-shift
Magnetic resonance imaging
Acetic acid
VX2 tumor
