麦门冬颗粒剂治疗幽门螺杆菌性胃炎200例疗效观察

Treatment of Helicobacter Pyloric Gastritis by Maimendong Keli:A Clinical Observation of 200 Cases

目的：观察麦门冬颗粒剂对幽门螺杆菌(Hp)性胃炎的临床疗效。方法：将320例Hp性胃炎患者随机分为2组。治疗组200例服用中药麦门冬颗粒刺(组成：麦冬、党参、大枣、粳米、佛手、白芍、法半夏、甘草),对照组120例采用西药奥美拉唑、阿莫西林胶囊、甲硝唑片三联用药。疗程均为4周,停药后观察2月。结果：症状总有效率治疗组为94．0%,对照组为78．3%；胃黏膜炎症改善率治疗组为93．0%,对照组为75．6%,2组比较,差异均有显著性意义(P＜0．05)。Hp根除率,治疗组为83．0%,对照组为81．7%,2组比较,差异无显著性意义(P＞0．05)。结论：麦门冬颗粒剂治疗Hp性胃炎疗效肯定。

Objective:To observe the clinical effect of Maimendong Keli(MK,麦门冬颗粒)for Helicobaeter pyloric gastritis(HPG).Methods:320 cases of HPG were allocated to 2 groups randomly.The treatment group(200 cases)was treated by MK(composed of Radix Ophiopogonis,Radix Codonopsis,Fructus Jujubae,fruc- tus Oryzae Sativae,Fructus Cirri Sarcodaetylis,Radix Paeoniae Alba,Rhizoom Pinel- liae Preparata and Radix Clyeyrrbizae),the control group(120 cases)by combination of omeprazole,amoxycillin capsule and metronidazole.4 weeks constituted the course of treatment,and the effects were observed after suspension of the medicines for 2 months.Results:The total effective rate of symptomatic relief was 94.0% and 78.3% in treatment group and control group respectively;the improvement rate of gastric mucosa inflammation was 93.0% and 75.6% in treatment group and control group respectively(P＜0.05).The eradication rote of HPG was 83.0% and 81.7% in treatment group and control group respectively(P＞0.05).Conclusion:MK pos- sesses marked effect for HPG.